Document Detail

Radiotherapy for craniopharyngioma in children: a national audit.
MedLine Citation:
PMID:  12602548     Owner:  NLM     Status:  MEDLINE    
A survey of current radiotherapy practices in the United Kingdom for treatment of craniopharyngioma in children was undertaken in view of the need to optimize control and minimize side effects in a patient group who can expect to survive for prolonged periods after treatment. Useable replies were received from 16 practitioners. A high level of conformity was reported in some areas but practice varied considerably in others. Thus whereas 15 employed magnetic resonance imaging (MRI) alone or with computed tomography (CT) to establish the gross tumour volume (GTV), six exclusively used pre-operative and seven exclusively used post-operative studies. Twelve added a margin of 1 cm to establish the planning target volume (PTV). Nine used CT planning. Fourteen gave radiation doses of between 50 and 55 Gy, but eight different dose/fractionation combinations were used. The most favoured regime (used by six) was 50 Gy in 30 fractions. Two centres provided written information on possible side effects of treatment. We suggest that it might prove helpful if a national treatment protocol was developed.
C R Jephcott; E M Sugden; T Foord
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical oncology (Royal College of Radiologists (Great Britain))     Volume:  15     ISSN:  0936-6555     ISO Abbreviation:  Clin Oncol (R Coll Radiol)     Publication Date:  2003 Feb 
Date Detail:
Created Date:  2003-02-26     Completed Date:  2003-04-29     Revised Date:  2008-03-10    
Medline Journal Info:
Nlm Unique ID:  9002902     Medline TA:  Clin Oncol (R Coll Radiol)     Country:  England    
Other Details:
Languages:  eng     Pagination:  10-3     Citation Subset:  IM    
Department of Clinical Oncology, Churchill Hospital, Old Road, Oxford OX3 7LJ, UK.
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MeSH Terms
Craniopharyngioma / diagnosis,  radiotherapy*
Dose Fractionation
Great Britain
Medical Audit
Pituitary Neoplasms / diagnosis,  radiotherapy*
Radiotherapy / methods,  statistics & numerical data

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