Document Detail

Radiosurgery as alternative treatment for skull base meningiomas.
MedLine Citation:
PMID:  11386818     Owner:  NLM     Status:  MEDLINE    
The effect of radiosurgical treatment of skull base meningiomas in 197 patients with a follow-up of at least 2 years was evaluated. Ninety-two of these patients had combined surgical and radiosurgical treatment, while Gamma Knife Radiosurgery (GKRS) was performed as primary treatment in 105 patients. Follow-up was available in 164 patients with intervals of 25-97 months (median 55 months) after GKRS. The imaging controls revealed decreased tumour size in 84 patients (51%), stable tumour volume in 76 ca ses (47%) and increased tumour size in 4 cases (2%). Neurological examinations showed improved neurological status in 58 cases (35%), stable clinical status in 100 patients (61%) and slight worsening in 6 cases (4%). Due to excellent tumour control rate, good clinical outcome and a low complication rate GKRS represents not only an attractive additional treatment option for basal meningiomas, but may even replace microsurgery in selected cases.
G Pendl; S Eustacchio; F Unger
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  8 Suppl 1     ISSN:  0967-5868     ISO Abbreviation:  J Clin Neurosci     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-06-01     Completed Date:  2001-10-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  Scotland    
Other Details:
Languages:  eng     Pagination:  12-4     Citation Subset:  IM    
Copyright Information:
Copyright 2001 Harcourt Publishers Ltd.
Department of Neurosurgery, Medical School and University, Graz, Austria.
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MeSH Terms
Aged, 80 and over
Follow-Up Studies
Meningeal Neoplasms / surgery*
Meningioma / surgery*
Middle Aged
Neoplasm Recurrence, Local / surgery
Retrospective Studies
Skull Base Neoplasms / surgery*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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