Document Detail


Radioprotective effect of whole-body hyperthermia on mice exposed to lethal doses of total-body gamma irradiation.
MedLine Citation:
PMID:  9014515     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The whole-body hyperthermia (40 degrees C, 1 hr) 20-48 hr prior to total-body irradiation (TBI) with 9 Gy gamma rays gave 80% protection as assessed by survival of the animals. However this was reduced to 50% when mice were irradiated 7 or 15 days after hyperthermia. The local hyperthermia (42 degrees C, 1 hr) given prior to irradiation, on the other hand, did not show any protective effect. The whole-body or local hyperthermia given after TBI had no protective effect on survival of animals.
Authors:
M S Patil; G S Kaklij; T B Poduval; B B Singh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Indian journal of experimental biology     Volume:  34     ISSN:  0019-5189     ISO Abbreviation:  Indian J. Exp. Biol.     Publication Date:  1996 Sep 
Date Detail:
Created Date:  1997-03-04     Completed Date:  1997-03-04     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0233411     Medline TA:  Indian J Exp Biol     Country:  INDIA    
Other Details:
Languages:  eng     Pagination:  842-4     Citation Subset:  IM    
Affiliation:
Radiation Biology and Biochemistry Division, Bhabha Atomic Research Centre, Bombay, India.
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MeSH Terms
Descriptor/Qualifier:
Animals
Gamma Rays
Hyperthermia, Induced*
Male
Mice
Radiation Tolerance*
Whole-Body Irradiation*

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