| Radiopacity of intracerebral hemorrhage correlates with perihemorrhagic edema. | |
| | |
MedLine Citation:
|
PMID: 21951394 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Background: Experimental evidence indicates that iron plays a key role in edema formation after intracerebral hemorrhage (ICH). We investigated the relationship between ICH radiopacity on CT as a marker of hematoma iron content and perihemorrhagic edema (PHE) after ICH. Methods: We retrospectively investigated patients with spontaneous lobar and ganglionic supratentorial ICH who received follow-up CT scans during the first 7 days after symptom onset (d1, d2-4, d5-7). Measurements of ICH and edema volumes were taken using a semiautomatic threshold-based volumetric algorithm. Radiopacity of the blood clot was determined using the mean Hounsfield unit (HU) count of the ICH. Results: A total of 117 patients aged 71.92 ± 11.55 years with spontaneous ICH (34.63 ± 32.44 ml) were included in the analysis. Mean ICH radiopacity was 59.7 ± 3.4 HU. We found significantly larger relative PHE at d2-4 (1.7 ± 0.9 vs. 1.3 ± 0.8; P = 0.032) and d5-7 (2.0 ± 1.3 vs. 1.3 ± 0.9; P = 0.007) and larger peak relative PHE (2.3 ± 1.6 vs. 1.6 ± 1.1; P = 0.006) in patients with ICH radiopacity >60 HU (n = 59), as compared to patients with ICH radiopacity <60 HU (n = 58). Conclusions: Higher ICH radiopacity, reflecting higher in vivo hematoma iron content, is associated with more PHE after ICH. |
| | |
Authors:
|
I Wagner; B Volbers; M J Hilz; S Schwab; A Doerfler; D Staykov |
Related Documents
:
|
1153944 - Alteration of esophageal peristalsis by pentagastrin in patients with diffuse esophagea... 18425214 - Beyond field effect: analysis of shrunken centroids in normal esophageal epithelia dete... 20601904 - Incidental gastric eosinophils in patients with eosinophilic esophagitis: do they matter? 3347754 - Benign esophagorespiratory fistulas in adults. 16409574 - Comparison of microbiological results of needle puncture vs. superficial swab in infect... 6888954 - Acupuncture therapy for tennis elbow. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-9-26 |
Journal Detail:
|
Title: European journal of neurology : the official journal of the European Federation of Neurological Societies Volume: - ISSN: 1468-1331 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
|
Created Date: 2011-9-28 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9506311 Medline TA: Eur J Neurol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
© 2011 The Author(s). European Journal of Neurology © 2011 EFNS. |
Affiliation:
|
Department of Neurology, University of Erlangen-Nuremberg, Erlangen, Germany Departments of Neurology, Medicine and Psychiatry, School of Medicine, New York University, New York, NY, USA Department of Neuroradiology, University of Erlangen-Nuremberg, Erlangen, Germany. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Functional and phenotypical alterations of polymorphonuclear cells in Sézary syndrome patients.
Next Document: Prevalence and severity of pulmonary hypertension in asymptomatic rural residents with schistosomal ...