| Radionuclide imaging study of long-term pulmonary function after lobectomy in children with congenital cystic lung disease. | |
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MedLine Citation:
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PMID: 19944215 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: We evaluated the long-term pulmonary function after lobectomy for congenital cystic lung disease, in both infants and children, using radionuclide imaging (RI). METHODS: We performed a retrospective review of 93 patients who underwent resection of cystic lung lesions between 1974 and 2001. The results of postoperative lung volume/perfusion scintigraphy at 1 (n = 64), 5 (n = 32), and 10 years (n = 18) after surgery (V1, 5, 10/Q1, 5, 10) and mean transit time (MTT-a marker for air-trapping) at 1, 5, and 10 years after surgery (MTT1, 5, 10) were compared with respect to age at operation, preoperative infection, underlying disease, and type of surgery. RESULTS: Patients who were younger than 1 year at the time of surgery showed a significantly lower MTT5 (1.09 +/- 0.08) and MTT10 (1.15 +/- 0.11) than patients who were older than 1 year at the time of surgery (MTT5, 1.49 +/- 0.67; MTT10, 1.54 +/- 0.33). The noninfected group had significantly higher Q10 and lower MTT10 values (P < .05) compared to the infected group. No significant differences were observed between patients with single lobe vs multiple lobe resection. CONCLUSIONS: The optimal age for surgery in patients with congenital cystic lung disease appears to be less than 1 year. |
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Authors:
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Koji Komori; Shoichiro Kamagata; Seiichi Hirobe; Miki Toma; Kenji Okumura; Mitsuru Muto; Shogo Kasai; Akira Hayashi; Mayumi Suenaga; Tomoo Miyakawa |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Journal of pediatric surgery Volume: 44 ISSN: 1531-5037 ISO Abbreviation: J. Pediatr. Surg. Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-11-30 Completed Date: 2010-02-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0052631 Medline TA: J Pediatr Surg Country: United States |
Other Details:
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Languages: eng Pagination: 2096-100 Citation Subset: IM |
Affiliation:
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Department of Surgery, Tokyo Metropolitan Kiyose Children's Hospital, Kiyose, Tokyo 204-8567, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Age Distribution Child Child, Preschool Cystic Adenomatoid Malformation of Lung, Congenital / surgery Cysts / congenital*, surgery* Female Follow-Up Studies Humans Infant Infant, Newborn Lung / abnormalities, radionuclide imaging*, surgery Lung Diseases / congenital*, surgery* Lung Volume Measurements Male Pneumonectomy / methods* Respiratory Function Tests / methods* Retrospective Studies Treatment Outcome Xenon Radioisotopes / diagnostic use |
| Chemical | |
Reg. No./Substance:
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0/Xenon Radioisotopes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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