Document Detail

Radionuclide imaging study of long-term pulmonary function after lobectomy in children with congenital cystic lung disease.
MedLine Citation:
PMID:  19944215     Owner:  NLM     Status:  MEDLINE    
PURPOSE: We evaluated the long-term pulmonary function after lobectomy for congenital cystic lung disease, in both infants and children, using radionuclide imaging (RI). METHODS: We performed a retrospective review of 93 patients who underwent resection of cystic lung lesions between 1974 and 2001. The results of postoperative lung volume/perfusion scintigraphy at 1 (n = 64), 5 (n = 32), and 10 years (n = 18) after surgery (V1, 5, 10/Q1, 5, 10) and mean transit time (MTT-a marker for air-trapping) at 1, 5, and 10 years after surgery (MTT1, 5, 10) were compared with respect to age at operation, preoperative infection, underlying disease, and type of surgery. RESULTS: Patients who were younger than 1 year at the time of surgery showed a significantly lower MTT5 (1.09 +/- 0.08) and MTT10 (1.15 +/- 0.11) than patients who were older than 1 year at the time of surgery (MTT5, 1.49 +/- 0.67; MTT10, 1.54 +/- 0.33). The noninfected group had significantly higher Q10 and lower MTT10 values (P < .05) compared to the infected group. No significant differences were observed between patients with single lobe vs multiple lobe resection. CONCLUSIONS: The optimal age for surgery in patients with congenital cystic lung disease appears to be less than 1 year.
Koji Komori; Shoichiro Kamagata; Seiichi Hirobe; Miki Toma; Kenji Okumura; Mitsuru Muto; Shogo Kasai; Akira Hayashi; Mayumi Suenaga; Tomoo Miyakawa
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  44     ISSN:  1531-5037     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-11-30     Completed Date:  2010-02-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2096-100     Citation Subset:  IM    
Department of Surgery, Tokyo Metropolitan Kiyose Children's Hospital, Kiyose, Tokyo 204-8567, Japan.
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MeSH Terms
Age Distribution
Child, Preschool
Cystic Adenomatoid Malformation of Lung, Congenital / surgery
Cysts / congenital*,  surgery*
Follow-Up Studies
Infant, Newborn
Lung / abnormalities,  radionuclide imaging*,  surgery
Lung Diseases / congenital*,  surgery*
Lung Volume Measurements
Pneumonectomy / methods*
Respiratory Function Tests / methods*
Retrospective Studies
Treatment Outcome
Xenon Radioisotopes / diagnostic use
Reg. No./Substance:
0/Xenon Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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