| Radionuclide assessment of myocardial fatty acid metabolism by PET and SPECT. | |
| | |
MedLine Citation:
|
PMID: 9420796 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Although fatty acid is a major energy source in the normal myocardium, fatty acid oxidation is easily suppressed in a variety of cardiac disorders. Therefore assessment of fatty acid metabolism may hold an important role for early detection of myocardial abnormalities and provide insights into cardiac pathologic states. C-11 palmitate is a well-established PET tracer to probe myocardial fatty acid metabolism. On the other hand, a variety of iodinated fatty acid compounds have been introduced for assessment of fatty acid metabolism with conventional gamma cameras. These include straight-chain, such as iodopheyl pentadecanoic acid (IPPA), and branch-chain fatty acid compounds, such as beta-methyl iodopheyl pentadecanoic acid (BMIPP). This review article includes the characterization of these tracers and clinical experiences with these tracers for detection and characterizing patients with ischemic heart disease and cardiomyopathy. |
| | |
Authors:
|
N Tamaki; Y Fujibayashi; Y Magata; Y Yonekura; J Konishi |
Related Documents
:
|
16460516 - A high-throughput screen for genes from castor that boost hydroxy fatty acid accumulati... 12915326 - Dietary fatty acids and coronary heart disease. 6295506 - The regulatory role of spermine and fatty acid in the interaction of amp deaminase with... 9572816 - Intramuscular fatty acid metabolism evaluated with stable isotopic tracers. 8387826 - The continuing development of gastric acid pump inhibitors. 19835376 - Fatty acid selectivity of lipases during acidolysis reaction between oleic acid and mon... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology Volume: 2 ISSN: 1071-3581 ISO Abbreviation: J Nucl Cardiol Publication Date: 1995 May-Jun |
Date Detail:
|
Created Date: 1998-02-06 Completed Date: 1998-02-06 Revised Date: 2006-05-06 |
Medline Journal Info:
|
Nlm Unique ID: 9423534 Medline TA: J Nucl Cardiol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 256-66 Citation Subset: IM |
Affiliation:
|
Department of Nuclear Medicine, Kyoto University Faculty of Medicine, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Animals, Domestic* Carbon Radioisotopes / diagnostic use Fatty Acids / diagnostic use Heart / radionuclide imaging* Humans Iodine Radioisotopes / diagnostic use Iodobenzenes / diagnostic use Myocardium / metabolism* Palmitic Acid / diagnostic use Tomography, Emission-Computed, Single-Photon* |
| Chemical | |
Reg. No./Substance:
|
0/Carbon Radioisotopes; 0/Fatty Acids; 0/Iodine Radioisotopes; 0/Iodobenzenes; 116754-87-1/iodofiltic acid; 57-10-3/Palmitic Acid; 80479-93-2/omega-(4-iodophenyl)pentadecanoic acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Attenuation correction in cardiac positron emission tomography and single-photon emission computed t...
Next Document: Gated planar technetium 99m-labeled sestamibi myocardial perfusion image inversion for quantitative ...