Document Detail

Radiology of gastrointestinal stromal tumors (GIST) and a case of Carney syndrome
MedLine Citation:
PMID:  10778462     Owner:  NLM     Status:  MEDLINE    
Gastrointestinal stromal tumors (GIST) represent an extremely rare group of tumors, which are mostly of smooth muscle origin like leiomyomas, leiomyosarcomas and leiomyoblastomas. With the introduction of immunohistochemical analysis an epithelioid and an autonomic nerve variant can be distinguished. The purpose of this review is to demonstrate the image morphological appearance of these rare tumors together with the pathology based upon a retrospective analysis of five of our own cases since 1997. There are no pathognomonic imaging findings for characterizing a gastrointestinal stromal tumor; however, it should be included in the differential diagnosis if one or multiple large, round or oval, well-delineated gastrointestinal tumors occur in combination with central necrosis. Carney's syndrome is characterized by the syndromal association of a gastrointestinal stromal tumor (originally: gastric leiomyosarcoma) with an extra-adrenal paraganglioma and a pulmonary chondroma. In this rare syndrome, the radiological approach is important to diagnose or rule out the--simultaneous or consecutive--appearance of at least two of the three tumor entities (GIST, extra-adrenal paraganglioma, pulmonary chondroma).
G Sigmund; C H Buitrago-Téllez; J Torhorst; W Steinbrich
Publication Detail:
Type:  Comparative Study; English Abstract; Journal Article; Review    
Journal Detail:
Title:  RöFo : Fortschritte auf dem Gebiete der Röntgenstrahlen und der Nuklearmedizin     Volume:  172     ISSN:  1438-9029     ISO Abbreviation:  Rofo     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-05-05     Completed Date:  2000-05-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7507497     Medline TA:  Rofo     Country:  GERMANY    
Other Details:
Languages:  ger     Pagination:  287-94     Citation Subset:  IM    
Abteilung Diagnostische Radiologie und Nuklearmedizin, Johannes Gutenberg-Universität Mainz.
Vernacular Title:
Radiologie des gastrointestinalen Stromatumors (GIST). Gleichzeitig ein Beitrag zum Carney-Syndrom.
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MeSH Terms
Chondrosarcoma / diagnosis,  pathology,  radiography*
Gastrointestinal Neoplasms / diagnosis,  pathology,  radiography*
Lung Neoplasms / diagnosis,  pathology,  radiography*
Middle Aged
Neoplasms, Multiple Primary / diagnosis,  pathology,  radiography*
Paraganglioma, Extra-Adrenal / diagnosis,  pathology,  radiography*
Rectal Neoplasms / diagnosis,  pathology,  radiography
Retroperitoneal Neoplasms / diagnosis,  pathology,  radiography
Stomach Neoplasms / diagnosis,  pathology,  radiography
Tomography, X-Ray Computed*

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