| Radiological and histological analysis of the structural changes in the rat parotid gland following release of Stensen's duct obstruction. | |
| | |
MedLine Citation:
|
PMID: 7835524 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Sialography is the preferred method for diagnosis and treatment planning in obstructive sialadenitis. Although many experimental studies have reported changes following duct obstruction, those following release of obstruction have not been examined. The present study was undertaken to clarify: (1) the relationship between sialographic and histological changes; (2) the effects of duration and pressure of obstruction on gland recovery; (3) the possibility of establishing those sialographic features which indicate the prognosis for gland recovery. Stensen's ducts of rat parotid glands were obstructed for two different periods and at three different pressures in order to induce varying degrees of degenerative changes in the gland. The structural alterations resulting from release of obstruction were investigated by means of qualitative and quantitative microsialography and histology. Gland structure was assessed visually from the latter and classified into six groups: normal, recovery, and slight, moderate and severe degeneration and fibrous. Microsialograms were evaluated based on these groups. Qualitatively, microsialograms of the operated glands had a stricture in the obstructed region and dilation of the major ducts. Histological differences between recovery and degeneration glands were reflected in the morphology of peripheral ducts. The former showed a branch-like morphology similar to that of the normal group, and the latter contained small granule-like structures. Quantitatively, dilation of major ducts in the recovery group decreased compared with the other operated groups. There were no distinct sialographic features in the degeneration and fibrous groups which correlated with the degree of degeneration observed histologically. Duration and pressure of obstruction were highly predictive for prognosis for recovery.(ABSTRACT TRUNCATED AT 250 WORDS) |
| | |
Authors:
|
M Shimizu; K Yoshiura; S Kanda |
Related Documents
:
|
7647804 - Estimation of the lag time between detrusor pressure- and flow rate-signals. 12853094 - The effect of anterior vaginal wall prolapse on urethral pressure profile. 12901404 - Bladder wall thickness on ultrasonographic cystourethrography: affecting factors and th... 1719684 - Change of external urethral sphincter function in prostatic patients. 20828214 - Electrochemical behavior of single-walled carbon nanotube supercapacitors under compres... 2694754 - Predictive and preventive pathology of cardiovascular diseases. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Dento maxillo facial radiology Volume: 23 ISSN: 0250-832X ISO Abbreviation: Dentomaxillofac Radiol Publication Date: 1994 Nov |
Date Detail:
|
Created Date: 1995-02-27 Completed Date: 1995-02-27 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7609576 Medline TA: Dentomaxillofac Radiol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 197-205 Citation Subset: D |
Affiliation:
|
Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Kyushu University, Fukuoka, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Male Microradiography Parotid Diseases / pathology, radiography* Parotid Gland / pathology, radiography* Prognosis Rats Rats, Inbred Lew Sialadenitis / pathology, surgery* Sialography / methods* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Observer performance in locating the bifurcation in mandibular molars on periapical radiographs.
Next Document: The effect of cathode ray tube display format on observer performance in dental digitized radiograph...