Document Detail


Radiologic and clinical findings of Behçet disease: comprehensive review of multisystemic involvement.
MedLine Citation:
PMID:  18603663     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Behçet disease is a chronic, relapsing, systemic disorder of unknown etiology, characterized by recurrent oral and genital ulcers, uveitis, and other clinical manifestations in multiple organ systems. Although the diagnosis is made on the basis of the combination of typical clinical symptoms, radiologic findings of Behçet disease show characteristic features of its involvement in the gastrointestinal, neurologic, cardiovascular, and thoracic organ systems. In the gastrointestinal tract, Behçet disease may produce various types of ulcers in the esophagus, stomach, and small and large intestines, as well as deeply penetrating ulcerations in the ileocecal region, with frequently accompanying enteric fistulas. Neurologic involvement includes typical and atypical parenchymal neurobehcet disease, dural sinus thrombosis, cerebral arterial aneurysm, occlusion, dissection, and meningitis. Vascular involvement is divided into three subsets including venous occlusion, arterial occlusion, and arterial aneurysm. Cardiac manifestations include intracardiac thrombus, endomyocardial fibrosis, periaortic pseudoaneurysm, and rupture of the sinus of Valsalva. Manifestations of Behçet disease in the thorax include pulmonary arterial aneurysm, pulmonary arterial thromboembolism, thrombosis in the superior vena cava, pulmonary infarction, hemorrhage, and vasculitis of the pleura and pericardium. These various manifestations of Behçet disease respond to steroid treatment; however, one of the characteristics of Behçet disease is the high rate of complications and recurrence after surgery. Familiarity with its various radiologic and clinical characteristics is essential in making an accurate early diagnosis and for prompt treatment of patients with Behçet disease.
Authors:
Eun Jin Chae; Kyung-Hyun Do; Joon Beom Seo; Seong Hoon Park; Joon-Won Kang; Yu Mi Jang; Jin Seong Lee; Jae-Woo Song; Koun-Sik Song; Jeong Hyun Lee; Ah Young Kim; Tae-Hwan Lim
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Publication Detail:
Type:  Journal Article; Review     Date:  2008-07-06
Journal Detail:
Title:  Radiographics : a review publication of the Radiological Society of North America, Inc     Volume:  28     ISSN:  1527-1323     ISO Abbreviation:  Radiographics     Publication Date:    2008 Sep-Oct
Date Detail:
Created Date:  2008-09-16     Completed Date:  2008-12-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8302501     Medline TA:  Radiographics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e31     Citation Subset:  IM    
Affiliation:
Department of Radiology, Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Songpa-gu, Seoul 138-736, Korea.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Behcet Syndrome / radiography*,  therapy*
Female
Humans
Male
Middle Aged
Multiple Organ Failure / radiography*,  therapy*
Young Adult

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