| Radioisotope synoviorthesis in rheumatoid arthritis. | |
| | |
MedLine Citation:
|
PMID: 375369 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Synoviorthesis with radioisotopes is indicated when joint inflammation is not totally controlled by drug prescription. Synoviorthesis should prevent osteoarticular destruction, especially in those cases where the patient does not feel any pain while taking analgesic and anti-inflammatory drugs. Several publications have shown the value of 90Y for treatment of the knee in rheumatoid arthritis. A dose of 4 mCi seems to be sufficient. For digital joints 169Er, a much weaker isotope, is used. Excellent and good results are obtained in 54.6% of cases. A recent double-blind study demonstrated a highly significant difference with saline (+ prednisolone acetate). Other joints, such as the wrist, elbow, shoulder, ankle or hip, can be treated with 198Au or, better, with 186Rh, which is an almost pure beta-emitter. Excellent and good results are seen in 50--60% of cases, depending on the joint. Treatment is well tolerated but patients younger than 40 years should not receive isotopes and the total dose administered should be less than 15 mCi. |
| | |
Authors:
|
C J Menkes |
Related Documents
:
|
21671699 - Economic impact of venous thromboembolism after hip and knee arthroplasty: potential im... 22027289 - Two important criteria for reducing the risk of postoperative ulcers at the gastrojejun... 21696569 - Safety and efficacy of radiation therapy as secondary prophylaxis for heterotopic ossif... 8120519 - Synovectomy for haemophilic arthropathy: 6-21 years of follow-up in 16 patients. 16516739 - Stabilization of the proximal ulnar stump in the sauvé-kapandji procedure by using the... 21779849 - Concomitant arginine-vasopressin and hydrocortisone therapy in severe septic shock: ass... 2397129 - Early and late results after repair of tetralogy of fallot. 22360669 - Efficacy of gemifloxacin for the treatment of experimental staphylococcus aureus kerati... 11249909 - Circadian variation of paroxysmal atrial fibrillation. pa3 investigators. atrial pacing... |
Publication Detail:
|
Type: Clinical Trial; Controlled Clinical Trial; Journal Article |
Journal Detail:
|
Title: Rheumatology and rehabilitation Volume: Suppl ISSN: 0300-3396 ISO Abbreviation: Rheumatol Rehabil Publication Date: 1979 |
Date Detail:
|
Created Date: 1979-07-25 Completed Date: 1979-07-25 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0355004 Medline TA: Rheumatol Rehabil Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 45-6 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Arthritis, Rheumatoid / radiotherapy* Clinical Trials as Topic Double-Blind Method Erbium / therapeutic use Finger Joint Humans Knee Joint Osmium Tetroxide / therapeutic use Placebos Radioisotopes / adverse effects, therapeutic use* Sodium Chloride Triamcinolone Acetonide / therapeutic use Yttrium Radioisotopes / therapeutic use |
| Chemical | |
Reg. No./Substance:
|
0/Placebos; 0/Radioisotopes; 0/Yttrium Radioisotopes; 20816-12-0/Osmium Tetroxide; 7440-52-0/Erbium; 76-25-5/Triamcinolone Acetonide; 7647-14-5/Sodium Chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Farmer's lung disease in Vermont.
Next Document: Use of the computer in teaching rheumatology. Trial application in the diagnosis of an adult polyart...