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Radioiodine I-131 for the therapy of graves' disease.
MedLine Citation:
PMID:  22589645     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Graves' disease is a common cause of hyperthyroidism. Treatment options for Graves' disease include antithyroid medication, surgery or radioactive iodine (I-31) or RAI. This review will focus on the approach to RAI therapy; discussing dose selection, patient preparation, and consideration before and after administering RAI, examining aspects of pre-treatment with antithyroid medication as well as discussing possible adverse events including hypothyroidism and possible worsening of thyroid-associated opthalmopathy. Follow-up is lifelong with the aim of ensuring the patient remains euthyroid or on replacement therapy if there is evidence of hypothyroidism. While there are controversies in treatment of thyrotoxicosis with RAI, with appropriate patient selection and regular follow-up, radioiodine is a safe and effective modality in achieving high cure rates.
Authors:
Malik Mumtaz; Lim Shueh Lin; Khaw Chong Hui; Amir Sharifuddin Mohd Khir
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Malaysian journal of medical sciences : MJMS     Volume:  16     ISSN:  1394-195X     ISO Abbreviation:  Malays J Med Sci     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2012-05-16     Completed Date:  2012-10-02     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101126308     Medline TA:  Malays J Med Sci     Country:  Malaysia    
Other Details:
Languages:  eng     Pagination:  25-33     Citation Subset:  -    
Affiliation:
Island Hospital, 308 Macalister Road, 10450 Penang, Malaysia.
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