Document Detail

Radioiodinated metaiodobenzylguanidine scintigraphy for pheochromocytoma. A false-positive case of adrenocortical adenoma and literature review.
MedLine Citation:
PMID:  8894669     Owner:  NLM     Status:  MEDLINE    
Radioiodinated metaiodobenzylguanidine (MIBG) scintigraphy is known for its high specificity in detecting pheochromocytoma and other tumors of neural crest origin. We describe herein the first case of a definite adrenocortical adenoma that demonstrated false-positive uptake on MIBG scintigraphy. In addition, we reviewed all 13 reported cases showing false-positive uptake, and suggest that careful evaluation is needed before diagnosing a 'silent' or 'asymptomatic' pheochromocytoma.
H Sone; Y Okuda; Y Nakamura; N Ishikawa; T Yamaoka; Y Kawakami; M Odawara; T Matsushima; K Kawai; K Yamashita
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Hormone research     Volume:  46     ISSN:  0301-0163     ISO Abbreviation:  Horm. Res.     Publication Date:  1996  
Date Detail:
Created Date:  1997-03-03     Completed Date:  1997-03-03     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0366126     Medline TA:  Horm Res     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  138-42     Citation Subset:  IM    
Department of Endocrinology and Metabolism, University of Tsukuba, Ibaraki, Japan.
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MeSH Terms
Adenoma / diagnosis,  pathology,  radionuclide imaging*
Adrenal Cortex Neoplasms / diagnosis,  pathology,  radionuclide imaging*
False Positive Reactions
Iodine Radioisotopes / diagnostic use
Iodobenzenes / diagnostic use
Pheochromocytoma / diagnosis,  pathology,  radionuclide imaging*
Tomography, X-Ray Computed
Reg. No./Substance:
0/Iodine Radioisotopes; 0/Iodobenzenes; 77679-27-7/3-Iodobenzylguanidine

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