Document Detail


Radioimmunoassay reveals no anti-male specificity in putative H-Y antisera.
MedLine Citation:
PMID:  7214743     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Putative anti-H-Y antisera have been examined for H-Y-specific antibody in a sensitive antiglobulin radioimmunoassay. All the sera tested were weakly bound by both male and female spleen cells. Absorption of the antisera with cells of either sex was equally effective in reducing the amount of antiglobulin bound revealing that their activity was not specific for H-Y gene products. The failure in this study to demonstrate H-Y-specific antibody is discussed.
Authors:
D N Crichton; C M Steel
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical and experimental immunology     Volume:  42     ISSN:  0009-9104     ISO Abbreviation:  Clin. Exp. Immunol.     Publication Date:  1980 Dec 
Date Detail:
Created Date:  1981-06-23     Completed Date:  1981-06-23     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0057202     Medline TA:  Clin Exp Immunol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  597-602     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Antibody Specificity
Autoantibodies / immunology
Female
Histocompatibility Antigens / immunology*
Immune Sera
Male
Mice
Mice, Inbred BALB C
Mice, Inbred C57BL
Radioimmunoassay
Sex Chromosomes / immunology*
Spleen / immunology
Y Chromosome / immunology*
Chemical
Reg. No./Substance:
0/Autoantibodies; 0/Histocompatibility Antigens; 0/Immune Sera
Comments/Corrections

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