| Radioimaging of the prostate and metastases of prostatic carcinoma with 99mTc-labelled prostatic acid phosphatase-specific antibodies and their Fab fragments. | |
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MedLine Citation:
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PMID: 6742767 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A radioimmunodetection technique using 99mTc-labelled polyclonal antibodies raised in rabbits against human prostate-specific acid phosphatase was used to detect metastases of prostatic carcinoma. All the metastases observed by X-rays or bone scintigraphy in the four patients with M1-disease were revealed by the novel technique employed. In addition, in one of the patients studied, a distinct incorporation of radioactivity was also observed in the left inferior scapular region, which was not seen by conventional bone scanning, but was later confirmed by X-ray studies to be a metastatic process. |
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Authors:
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P Vihko; J Heikkilä; M Kontturi; L Wahlberg; R Vihko |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Annals of clinical research Volume: 16 ISSN: 0003-4762 ISO Abbreviation: Ann. Clin. Res. Publication Date: 1984 |
Date Detail:
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Created Date: 1984-08-01 Completed Date: 1984-08-01 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0220042 Medline TA: Ann Clin Res Country: FINLAND |
Other Details:
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Languages: eng Pagination: 51-2 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acid Phosphatase
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immunology Bone Neoplasms / radionuclide imaging, secondary* Humans Immunoglobulin Fab Fragments* Immunoglobulins* Male Prostate / radionuclide imaging* Prostatic Neoplasms / radionuclide imaging* Technetium / diagnostic use* |
| Chemical | |
Reg. No./Substance:
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0/Immunoglobulin Fab Fragments; 0/Immunoglobulins; 7440-26-8/Technetium; EC 3.1.3.2/Acid Phosphatase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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