Document Detail

Radiographic signs of renal disease in rabbits.
MedLine Citation:
PMID:  17558026     Owner:  NLM     Status:  MEDLINE    
The radiological features of 65 rabbits with suspected renal disease are reviewed. The radiological features included a generalised increase in bone opacity (osteosclerosis), renomegaly, nephroliths, ureteroliths and soft tissue mineralisation. One or more of these changes were present on radiographs of 57 of the 65 rabbits. Renal disease was suspected because of the clinical signs and the presence of kidney stones and/or high blood concentrations of urea and creatinine. Significant renal disease was confirmed in 14 cases that were examined postmortem. Blood urea and creatinine concentrations were measured in 47 cases but not all the rabbits had high levels of both. Blood calcium concentration was high in 33 of the 38 rabbits in which it was measured. Serum phosphate was high in 17 and low in five of 34 rabbits in which it was measured. Hyperphosphataemia was associated with generalised osteosclerosis and aortic calcification. Rabbits with osteosclerosis were thin, depressed and unwilling to move. Thirty-eight of 41 rabbits that were tested were seropositive for antibodies to Encephalitozoon cuniculi. Histological lesions suggestive of E cuniculi infection were found in all 13 cases that were examined postmortem, although the organisms were visible in only one case.
F Harcourt-Brown
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Veterinary record     Volume:  160     ISSN:  0042-4900     ISO Abbreviation:  Vet. Rec.     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-06-11     Completed Date:  2007-07-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0031164     Medline TA:  Vet Rec     Country:  England    
Other Details:
Languages:  eng     Pagination:  787-94     Citation Subset:  IM    
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MeSH Terms
Calcium / blood
Creatinine / blood
Encephalitozoon cuniculi / isolation & purification
Encephalitozoonosis / complications,  veterinary*
Kidney Calculi / blood,  radiography,  veterinary*
Kidney Diseases / blood,  radiography,  veterinary*
Phosphates / blood
Urea / blood
Uremia / metabolism
Reg. No./Substance:
0/Phosphates; 57-13-6/Urea; 60-27-5/Creatinine; 7440-70-2/Calcium

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