Document Detail

Radiographic repair in three Japanese patients with rheumatoid arthritis treated with bucillamine.
MedLine Citation:
PMID:  19711150     Owner:  NLM     Status:  MEDLINE    
Bucillamine (Bc) is a cysteine derivative with two SH groups, and a homolog of D-penicillamine, a disease-modifying antirheumatic drug (DMARD) widely used in Japan. However, it remains unclear whether Bc repairs bone erosion in patients with RA. Here, we treated three RA patients with Bc who subsequently showed radiographic repair of erosions and cysts.
Yuki Nanke; Masako Iwatani; Tsuyoshi Kobashigawa; Toru Yago; Hisashi Yamanaka; Shigeru Kotake
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-08-27
Journal Detail:
Title:  Modern rheumatology / the Japan Rheumatism Association     Volume:  19     ISSN:  1439-7609     ISO Abbreviation:  Mod Rheumatol     Publication Date:  2009  
Date Detail:
Created Date:  2009-12-09     Completed Date:  2010-02-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100959226     Medline TA:  Mod Rheumatol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  681-6     Citation Subset:  IM    
Institute of Rheumatology, Tokyo Women's Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo, 162-0054, Japan.
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MeSH Terms
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Arthritis, Rheumatoid / drug therapy*,  pathology,  radiography*
Bone and Bones / pathology*,  radiography*
Cysteine / analogs & derivatives*,  therapeutic use
Disease Progression
Joints / pathology
Middle Aged
Recovery of Function
Severity of Illness Index
Treatment Outcome
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 52-90-4/Cysteine; 65002-17-7/bucillamine

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