Document Detail


Radiographic changes in primary osteogenic sarcoma following intensive chemotherapy. Radiological-pathological correlation in 63 patients.
MedLine Citation:
PMID:  6978499     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sixty-three patients with osteogenic sarcoma of the long bones, all of whom were treated with chemotherapy, demonstrated striking and unusual radiographic changes. Patients with a "good" radiographic response (48%) showed the most dramatic changes, including medullary sclerosis, prominent periosteal new bone formation, and disappearance of the soft-tissue mass; and these findings correlated well with the histological grading of the surgical specimens. Radiographic evaluation of patients receiving chemotherapy for osteogenic sarcoma is a valuable method of assessing response.
Authors:
J Smith; R T Heelan; A G Huvos; B Caparros; G Rosen; C Urmacher; J F Caravelli
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Radiology     Volume:  143     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1982 May 
Date Detail:
Created Date:  1982-06-14     Completed Date:  1982-06-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  355-60     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Amputation
Antineoplastic Agents / administration & dosage*
Bone Neoplasms / pathology,  radiography*,  therapy
Child
Child, Preschool
Drug Therapy, Combination
Female
Humans
Leg
Leucovorin / administration & dosage
Male
Methotrexate / administration & dosage
Osteosarcoma / pathology,  radiography*,  therapy
Chemical
Reg. No./Substance:
0/Antineoplastic Agents; 58-05-9/Leucovorin; 59-05-2/Methotrexate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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