Document Detail

Radiographic analysis of fusion progression following one-level cervical fusion with or without plate fixation.
MedLine Citation:
PMID:  17665339     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Anterior cervical discectomy and fusion (ACDF) using bone graft or a cage with plate fixation is an accepted technique for the treatment of symptomatic degenerative disc disease. It is, however, debatable whether a plate is really necessary to increase the progress of fusion. Thus, the aim of this randomized and controlled prospective study was to evaluate whether ACDF with a cage and anterior plate fixation results in a greater progress of fusion compared with ACDF using a stand-alone cage. METHODS: 37 candidates for ACDF were treated either with a stand-alone cage (study group) or with a cage+plate fixation (control group). 19 patients were randomized to be stabilized with a stand-alone cage and 18 patients were treated with a cage and additional anterior plate fixation. The progress of cervical fusion over time was compared by radiostereometric analysis (RSA). Follow-up examinations pre- and postoperatively were done using the Visual Analogue Scale (VAS) for neck and arm pain. Radiographic assessment of fusion using an RSA-control was done after one, six and twelve weeks, as well as after six months, and one and two years postoperatively. Mann-Whitney test for unpaired values was used to determine the statistical differences in residual intervertebral motion. RESULTS: Three-dimensional analysis of segmental motion (left-right, cranio-caudal, and posterior-anterior) did not reveal any statistical differences between both groups at any examination time postoperatively ( P>0.05). The VAS score did not differ between the groups ( P>0.05). CONCLUSION: Anterior plate fixation did not demonstrate an improvement in the progress of fusion in one-level ACDF.
A Nabhan; D Pape; T Pitzen; W-I Steudel; F Bachelier; J Jung; F Ahlhelm
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial     Date:  2007-07-30
Journal Detail:
Title:  Zentralblatt für Neurochirurgie     Volume:  68     ISSN:  0044-4251     ISO Abbreviation:  Zentralbl. Neurochir.     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-08-31     Completed Date:  2007-10-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0413646     Medline TA:  Zentralbl Neurochir     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  133-8     Citation Subset:  IM    
Department of Neurosurgery, University of Saarland, Homburg, Germany.
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MeSH Terms
Bone Plates*
Cervical Vertebrae / radiography*,  surgery*
Internal Fixators*
Intervertebral Disk / pathology,  surgery
Middle Aged
Neck Pain / etiology,  psychology
Pain / epidemiology,  psychology
Pain Measurement
Prospective Studies
Spinal Fusion*
Spine / radiography*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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