Document Detail

Radiofrequency ablation of ventricular myocardium using active fixation and passive contact catheter delivery systems.
MedLine Citation:
PMID:  2741798     Owner:  NLM     Status:  MEDLINE    
This study examined the qualitative and quantitative effects of radiofrequency energy using active fixation and passive contact catheter delivery systems on normal bovine atrium and ventricle and diseased human ventricle in vitro. Two active fixation (custom screw-in or suction electrode) catheters and two passive contact (custom ring or standard electrode) catheters were used with a 500 kHz radiofrequency current generator. Linear regression analysis between lesion dimensions and power output showed excellent correlation coefficients for all catheter delivery systems except the suction catheter. Lesion sizes also increased with duration of radiofrequency energy delivery at low power using the USCI quadripolar catheter. Lesion size in diseased human ventricle was considerably smaller than in the normal ventricle. Comparison of induced lesion dimensions using pulsed and continuous delivery modes showed only minor differences. Tissue impedance was relatively constant during energy delivery. Arcing was associated with a sudden increase in voltage and impedance and a sudden decline in current. This was most frequently observed at high power and with the suction electrode catheter. The use of high (50 W) power output and prolonged application (up to 180 seconds) in atrium and ventricle did not induce perforation. We conclude that a variety of catheter delivery systems can be used for effective radiofrequency energy delivery and ablation in atrial and ventricular myocardium in the pulsed or continuous mode. Impedance changes during radiofrequency ablation cannot be used to guide the extent of ablation but do detect arcing during the procedure.
H L An; S Saksena; M Janssen; P Osypka
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Publication Detail:
Type:  In Vitro; Journal Article    
Journal Detail:
Title:  American heart journal     Volume:  118     ISSN:  0002-8703     ISO Abbreviation:  Am. Heart J.     Publication Date:  1989 Jul 
Date Detail:
Created Date:  1989-08-01     Completed Date:  1989-08-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370465     Medline TA:  Am Heart J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  69-77     Citation Subset:  AIM; IM    
UMDNJ-New Jersey Medical School & Newark Beth Israel Medical Center.
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MeSH Terms
Heart / radiation effects*
Heart Catheterization / instrumentation*
Myocardium / pathology
Radio Waves*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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