Document Detail


Radiofrequency ablation to treat non-small cell lung cancer and pulmonary metastases.
MedLine Citation:
PMID:  18222217     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Radiofrequency ablation is being reported with increasing frequency for the treatment of lung tumors. Several studies have demonstrated that this is a feasible and safe approach. Intermediate outcomes are now becoming available. Although tumors up to 5 cm in size can be effectively treated with radiofrequency ablation, results are better for smaller tumors (3 cm or less). This review describes the techniques, available ablation devices, and the potential role of radiofrequency ablation for non-small cell lung cancer (NSCLC) and pulmonary metastases. Resection (lobar or sublobar) should remain the standard therapy for NSCLC. Radiofrequency ablation may be better than conventional external-beam radiation for the treatment of the high-risk individual with NSCLC. Preliminary results for pulmonary metastases are similar to those reported after resection. In addition, patients with pulmonary metastases have been demonstrated to develop recurrences even after thoracotomy and bimanual palpation of the lung. Radiofrequency ablation may be an alternative to resection for the patient with small-diameter pulmonary metastases, and future study of this may be indicated.
Authors:
Hiran C Fernando
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  85     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2008 Feb 
Date Detail:
Created Date:  2008-01-28     Completed Date:  2008-03-11     Revised Date:  2009-06-30    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  S780-4     Citation Subset:  AIM; IM    
Affiliation:
Department of Cardiothoracic Surgery, Boston Medical Center, Boston University, Boston, Massachusetts 02118, USA. hiran.Fernando@bmc.org
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MeSH Terms
Descriptor/Qualifier:
Adult
Age Factors
Aged
Aged, 80 and over
Carcinoma, Non-Small-Cell Lung / mortality,  secondary*,  surgery*
Catheter Ablation / methods*
Female
Follow-Up Studies
Humans
Lung Neoplasms / mortality,  pathology,  secondary*,  surgery*
Male
Middle Aged
Neoplasm Invasiveness / pathology
Neoplasm Metastasis
Neoplasm Staging
Patient Selection
Risk Assessment
Sex Factors
Surgical Procedures, Minimally Invasive / methods
Survival Analysis
Treatment Outcome
Comments/Corrections
Comment In:
Ann Thorac Surg. 2009 Jul;88(1):351-2   [PMID:  19559273 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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