Document Detail


Radiofrequency ablation of metastatic pheochromocytoma.
MedLine Citation:
PMID:  19875067     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In the present report on the preliminary safety and effectiveness of radiofrequency (RF) ablation for pheochromocytoma metastases, seven metastases were treated in six patients (mean size, 3.4 cm; range, 2.2-6 cm). alpha- and beta-adrenergic and catecholamine synthesis inhibition and intraprocedural anesthesia monitoring were used. Safety was assessed by recording ablation-related complications. Complete ablation was defined as a lack of enhancement within the ablation zone on follow-up computed tomography. No serious adverse sequelae were observed. Complete ablation was achieved in six of seven metastases (mean follow-up, 12.3 months; range, 2.5-28 months). In conclusion, RF ablation may be safely performed for metastatic pheochromocytoma given careful attention to peri-procedural management.
Authors:
Aradhana M Venkatesan; Julia Locklin; Edwin W Lai; Karen T Adams; Antonio Tito Fojo; Karel Pacak; Bradford J Wood
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, N.I.H., Intramural    
Journal Detail:
Title:  Journal of vascular and interventional radiology : JVIR     Volume:  20     ISSN:  1535-7732     ISO Abbreviation:  J Vasc Interv Radiol     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-10-30     Completed Date:  2010-01-06     Revised Date:  2013-04-18    
Medline Journal Info:
Nlm Unique ID:  9203369     Medline TA:  J Vasc Interv Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1483-90     Citation Subset:  IM    
Affiliation:
Center for Interventional Oncology, Department of Radiology and Imaging Sciences, National Institutes of Health Clinical Center, Bethesda, Maryland 20892, USA. venkatesana@cc.nih.gov
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MeSH Terms
Descriptor/Qualifier:
Adrenal Gland Neoplasms / surgery*
Adult
Aged
Bone Neoplasms / secondary*,  surgery*
Catheter Ablation / methods*
Female
Humans
Liver Neoplasms / secondary*,  surgery*
Male
Middle Aged
Pheochromocytoma / secondary*,  surgery*
Treatment Outcome
Grant Support
ID/Acronym/Agency:
Z99 CL999999/CL/CLC NIH HHS; ZIA CL040011-03/CL/CLC NIH HHS; ZIA CL040015-02/CL/CLC NIH HHS; ZID BC011242-02/BC/NCI NIH HHS
Comments/Corrections

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