| Radiofrequency catheter ablation of ventricular arrhythmias in patients with hypertrophic cardiomyopathy: safety and feasibility. | |
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MedLine Citation:
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PMID: 20493276 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Management of ventricular tachycardia (VT) in patients with hypertrophic cardiomyopathy (HCM) is challenging. OBJECTIVE: The purpose of this study is to assess the value of radiofrequency catheter ablation (RFCA) for the treatment of the VTs in the setting of HCM. METHODS: Twenty-two patients (18 with ICD) with HCM and multiple episodes of VTs resistant to medical therapy underwent RFCA with an open irrigation catheter. Epicardial access was obtained if required. All patients were followed for at least 1 year after RFCA. RESULTS: Mean age was 50.4 +/- 15.3, and mean ejection fraction was 34.3% +/- 9.8%. RFCA was performed endocardially in all patients, while epicardial radiofrequency applications were needed in 13 patients. A previous endocardial ablation was unsuccessful in six patients. At 20 +/- 9 months of follow-up, elimination of VTs reached 73%. No major complication was observed during and after the procedures in all patients. CONCLUSION: Catheter ablation of VTs in patients with hypertrophic cardiomyopathy refractory to medical therapy is safe, feasible, and successful in eliminating VT. Epicardial VT mapping and ablation should be considered as an important access option for the treatment of these patients to increase the success rate. |
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Authors:
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Pasquale Santangeli; Luigi Di Biase; Dhanunjay Lakkireddy; J David Burkhardt; Jayasree Pillarisetti; Yoav Michowitz; Javier E Sanchez; Rodney Horton; Prasant Mohanty; G Joseph Gallinghouse; Antonio Dello Russo; Michela Casella; Gemma Pelargonio; Pietro Santarelli; Atul Verma; Calambur Narasimhan; Kalyanam Shivkumar; Andrea Natale |
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Publication Detail:
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Type: Journal Article Date: 2010-05-19 |
Journal Detail:
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Title: Heart rhythm : the official journal of the Heart Rhythm Society Volume: 7 ISSN: 1556-3871 ISO Abbreviation: Heart Rhythm Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-07-26 Completed Date: 2010-12-15 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101200317 Medline TA: Heart Rhythm Country: United States |
Other Details:
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Languages: eng Pagination: 1036-42 Citation Subset: IM |
Copyright Information:
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Copyright 2010 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Texas Cardiac Arrhythmia Institute at St. David Medical Center, University of Texas, Austin, Texas 78705, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Cardiomyopathy, Hypertrophic / complications* Catheter Ablation* Female Humans Male Middle Aged Tachycardia, Ventricular / etiology, surgery* Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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