Document Detail

Radiofrequency Ablation of Benign Thyroid Nodules Does Not Affect Thyroid Function in Patients with Previous Lobectomy.
MedLine Citation:
PMID:  23013110     Owner:  NLM     Status:  Publisher    
Background: Surgical management of symptomatic benign thyroid nodules in patients with previous lobectomy poses a dilemma for physicians. Radiofrequency (RF) ablation may provide a treatment option that avoids surgery and preserves thyroid function. We evaluated whether RF ablation of benign thyroid nodules affects thyroid functions in patients with previous lobectomy. Methods: A total of 11 patients with 14 thyroid nodules were enrolled using the following criteria: (1) having a predominantly solid nodule; (2) reporting pressure symptoms or cosmetic problems; (3) cytological confirmation of benignancy; (4) no malignant features detected using ultrasound; (5) serum thyroid hormone and thyrotropin (TSH) levels within normal limits; and (6) refusal of or ineligibility for surgery. Thyroid functions, nodule volumes, and clinical concerns were evaluated before RF ablation and during follow-up after RF ablation. Results: The mean follow-up duration after RF ablation was 43.7 ± 30.7 months (range, 7-92 months). The mean nodule volume was 9.7 ml (0.9-57.6 ml) before the procedure, and was significantly decreased at the last follow-up (P < 0.001) with a mean volume reduction rate of 87.2 %. The mean symptom score (P = 0.003) and cosmetic score (P = 0.003) were both significantly decreased at the last follow-up. Levels of TSH, free thyroxine, and triiodothyronine were not significantly different prior to treatment and at the last follow-up (P > 0.05), and remained normal in all cases. Conclusions: In patients with previous lobectomy, RF ablation should be considered as a first-line treatment for symptomatic benign thyroid nodules to preserve thyroid functions.
Eun Ju Ha; Jung Hwan Baek; Jeong Hyun Lee; Jin Yong Sung; Ducky Lee; Jae Kyun Kim; Yong Kee Shong
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-26
Journal Detail:
Title:  Thyroid : official journal of the American Thyroid Association     Volume:  -     ISSN:  1557-9077     ISO Abbreviation:  Thyroid     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9104317     Medline TA:  Thyroid     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
University of Ulsan College of Medicine, Asan Medical Center, Department of Radiology and Research Institute of Radiology, Seoul, Korea, Republic of;
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