Document Detail


Radioautographic study of the axonal transport of proteins into the sensory nerve endings of avian mechanoreceptors.
MedLine Citation:
PMID:  6188076     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The axonal transport of proteins to the nerve endings of Herbst and Grandry sensory receptors has been investigated by electron-microscope radioautography. Soon after the injection of [3H]leucine into the trigeminal ganglia of young ducks, labeled proteins are conveyed along the suborbital sensory nerves to the sensory nerve endings at rates of at least 200-280 mm/day. Most of these rapidly transported proteins accumulate in areas containing vesicles of various kinds and along the axolemmal region. Later, the bulk of labeled proteins migrate along the axons at rates of about 15 mm/day and are distributed mainly to the mitochondria. A small portion of labeled material is transferred to the adjoining modified Schwann and specialized Grandry receptor cells. It is concluded that the transport of proteins from sensory ganglia to sensory nerve endings of mechanoreceptors is conveyed at fast and intermediate rates and is mainly used for the renewal of vesicles, axolemmal constituents and mitochondria.
Authors:
C N Chouchkov; D V Markov; G P Galabov
Related Documents :
2475836 - Toxic neurofilamentous axonopathies and fast anterograde axonal transport. i. the effec...
12433796 - Rlip76, a novel transporter catalyzing atp-dependent efflux of xenobiotics.
11278876 - Exchangeability of n termini in the ligand-gated porins of escherichia coli.
7654756 - A trans-membrane pore can account for protein movement across zymogen granule membranes.
9514726 - Rapid refinement of protein interfaces incorporating solvation: application to the dock...
14584586 - The puf family of rna-binding proteins: does evolutionarily conserved structure equal c...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neuroscience     Volume:  8     ISSN:  0306-4522     ISO Abbreviation:  Neuroscience     Publication Date:  1983 Jan 
Date Detail:
Created Date:  1983-05-27     Completed Date:  1983-05-27     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7605074     Medline TA:  Neuroscience     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  133-42     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Autoradiography
Axonal Transport*
Ducks
Leucine / metabolism
Mechanoreceptors / metabolism*
Microscopy, Electron
Nerve Fibers / metabolism
Nerve Tissue Proteins / metabolism*
Trigeminal Ganglion / metabolism
Trigeminal Nerve / metabolism*
Chemical
Reg. No./Substance:
0/Nerve Tissue Proteins; 61-90-5/Leucine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effect of intrathecal capsaicin analogues on the immunofluorescence of peptides and serotonin in the...
Next Document:  Ultrastructural and histochemical abnormalities of skeletal muscle in patients with chronic vitamin ...