Document Detail


Radical trachelectomy in early stage carcinoma of the cervix: outcome as judged by recurrence and fertility rates.
MedLine Citation:
PMID:  11510717     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The recurrence and fertility rates in 30 women undergoing radical trachelectomy for early stage invasive cervical cancer at St Bartholomew's and Royal Marsden Hospital were reviewed. There were no recurrences, and the mean follow up was 23 months (range 1-64 months). Of 13 women trying to have a baby, eight had conceived with a total of 14 pregnancies and nine live births. Two were still trying and three were experiencing sub-fertility. There were seven premature deliveries and one late miscarriage. Six of the preterm births and the late miscarriage were associated with prelabour spontaneous rupture of membranes. This conservative yet locally radical procedure for a highly selected group of women who wished to preserve their fertility appears to offer a safe alternative to radical hysterectomy in early invasive cervical cancer.
Authors:
J H Shepherd; T Mould; D H Oram
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Publication Detail:
Type:  Journal Article; Multicenter Study    
Journal Detail:
Title:  BJOG : an international journal of obstetrics and gynaecology     Volume:  108     ISSN:  1470-0328     ISO Abbreviation:  BJOG     Publication Date:  2001 Aug 
Date Detail:
Created Date:  2001-08-20     Completed Date:  2002-01-03     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  100935741     Medline TA:  BJOG     Country:  England    
Other Details:
Languages:  eng     Pagination:  882-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Gynaecological Oncology, St Bartholomew's Hospital, East London Cancer Centre, London, UK.
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / surgery
Carcinoma / surgery*
Carcinoma, Adenosquamous / surgery
Carcinoma, Squamous Cell / surgery
Cervix Uteri / surgery*
Female
Humans
Neoplasm Recurrence, Local / etiology*
Pregnancy / statistics & numerical data*
Treatment Outcome
Uterine Cervical Neoplasms / surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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