| Radiation, retardation and the developing brain: time is the crucial variable. | |
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MedLine Citation:
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PMID: 18394093 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Widespread radiation is a threat unique to the modern world. A recent report reveals that sub-clinical damage to human foetuses between 8 and 25 weeks of gestation can result in cognitive deficits still manifest 16-18 years after birth. These previously unrecognised, long-term effects are apparently produced by a relatively short pulse of exposure to radioactive fallout at levels that were previously thought not to be deleterious. This idea is plausible given the nature of the developmental events occurring in the brain during this period of gestation. CONCLUSION: This exposed population should be examined for other neurological and psychiatric syndromes. If these findings are corroborated, in the event of future radiation exposures, steps should be taken to shield pregnant women who are within this window of vulnerability. |
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Authors:
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Richard S Nowakowski; Nancy L Hayes |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta paediatrica (Oslo, Norway : 1992) Volume: 97 ISSN: 0803-5253 ISO Abbreviation: Acta Paediatr. Publication Date: 2008 May |
Date Detail:
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Created Date: 2008-04-08 Completed Date: 2008-08-13 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9205968 Medline TA: Acta Paediatr Country: Norway |
Other Details:
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Languages: eng Pagination: 527-31 Citation Subset: IM |
Affiliation:
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Department of Neuroscience and Cell Biology, UMDNJ-Robert Wood Johnson Medical School, 675 Hoes Lane, Piscataway, NJ 08873, USA. rsn@umdnj.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Cell Cycle / radiation effects* Chernobyl Nuclear Accident* Female Fetal Development / radiation effects* Gestational Age Humans Infant, Newborn Mental Retardation / etiology* Neocortex / growth & development* Pregnancy Sweden Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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