|Radiation-induced arterial injuries.|
|PMID: 6823669 Owner: NLM Status: MEDLINE|
|In a 20-year period from 1961 to 1981 at the University of Kentucky Medical Center, there were 20 patients with vascular lesions directly attributable to irradiation. Two distinct patterns of arterial injury attributable to radiotherapy were identified--arterial disruption and occlusion. Arterial disruption occurred in 12 patients--11 carotid blowouts and 1 iliac artery rupture. Two patients underwent prophylactic carotid artery ligation for impending rupture. In the 11 carotid artery ruptures, ligation of the artery in nine patients resulted in stroke or death in five patients. Iliac artery disruption necessitated ligation, which eventually led to severe ischemia requiring hip disarticulation. Unusual arterial stenosis or occlusion occurred in six patients 7 to 24 years after irradiation. Three patients had severe stenosis or occlusion of the common, internal, or external carotid arteries leading to cerebrovascular insufficiency. Three other patients with focal stenosis of the iliofemoral region were successfully treated with bypass grafting.|
|R A McCready; G L Hyde; B A Bivins; S S Mattingly; W O Griffen|
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|Type: Case Reports; Journal Article|
|Title: Surgery Volume: 93 ISSN: 0039-6060 ISO Abbreviation: Surgery Publication Date: 1983 Feb|
|Created Date: 1983-03-11 Completed Date: 1983-03-11 Revised Date: 2005-11-17|
Medline Journal Info:
|Nlm Unique ID: 0417347 Medline TA: Surgery Country: UNITED STATES|
|Languages: eng Pagination: 306-12 Citation Subset: AIM; IM|
|APA/MLA Format Download EndNote Download BibTex|
Arterial Occlusive Diseases / etiology*
Arteries / radiation effects*
Carcinoma, Squamous Cell / radiotherapy
Carotid Arteries / radiation effects, radiography
Cerebrovascular Disorders / etiology
Femoral Artery / surgery
Hip Dislocation / etiology
Iliac Artery / radiation effects
Ischemia / etiology
Ligation / adverse effects
Mouth Neoplasms / radiotherapy
Radiation Injuries / etiology*
Radiotherapy / adverse effects*
Rupture, Spontaneous / prevention & control
Saphenous Vein / transplantation
Uterine Cervical Neoplasms / radiotherapy
Vocal Cords / pathology
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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