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Radiation-induced adult medulloblastoma: a two-case report and review of the literature.
MedLine Citation:
PMID:  20936325     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Radiation-induced medulloblastoma is an exceedingly rare phenomenon for which treatment standards have not been established. The literature suggests that these tumors are high grade with aggressive behavior. We report two cases of radiation-induced medulloblastoma which have been treated with full dose re-irradiation with curative intent. In both cases, treatment toxicity and tumor progression proved to be insurmountable obstacles. Further reports are necessary in order to fully characterize this clinical entity so that more effective therapies may be sought.
Authors:
Michael D Chan; Albert Attia; Stephen B Tatter; Glenn Lesser; Michael E Zapadka; Ryan T Mott; Annette Carter; Kevin P McMullen; Edward G Shaw; Thomas E Ellis
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Publication Detail:
Type:  Journal Article     Date:  2010-10-09
Journal Detail:
Title:  Journal of neuro-oncology     Volume:  103     ISSN:  1573-7373     ISO Abbreviation:  J. Neurooncol.     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-06-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309335     Medline TA:  J Neurooncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  745-9     Citation Subset:  IM    
Affiliation:
Department of Radiation Oncology, Wake Forest University Health Sciences-Baptist Medical Center, 1 Medical Center Blvd, Winston-Salem, NC, 27103, USA, mchan@wfubmc.edu.
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