Document Detail


Radiation exposure in 212 very low and extremely low birth weight infants.
MedLine Citation:
PMID:  19948626     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: We determined the frequency and estimated effective radiation dose (E) from conventional diagnostic radiographs for infants who had birth weight of <or=1500 g (very low birth weight [VLBW] infants) and were treated in a NICU. METHODS: Entrance skin doses were experimentally measured for all standard weight-dependent exposure settings. For each radiograph in the radiologic file, the exposed area on the film was measured manually. Together with clinical data obtained from the Vermont Oxford Network, medical charts, and radiologic files, we estimated E. E values per radiograph and per child were compared with recommended reference values and annual natural background radiation (NBR). We used reference data to estimate the risk for radiation-induced cancers. RESULTS: Of 212 VLBW infants, 194 required at least 1 conventional radiograph. Measured entrance skin dose varied between 11.8 and 15.0 microGy. Calculated E received was 16 microsievert (microSv; median) per radiograph and 71.5 microSv (median) per infant for the whole stay. Infants with birth weight <or=750 g, length of stay >or=16 weeks, congenital malformations, or oxygen dependence for >or=36 weeks were at risk for high numbers of radiographs and high radiation dose. Compared with the annual NBR, the median of 4 radiographs per infant contributes 12 days of NBR. We estimated that only 1 of 60000 NICU-treated VLBW infants will develop a fatal malignancy up to 15 years of age. CONCLUSIONS: We found that NICU-treated VLBW infants had low radiation exposure compared with the annual NBR.
Authors:
Kathrin Puch-Kapst; Ralf Juran; Brigitte Stoever; Roland R Wauer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pediatrics     Volume:  124     ISSN:  1098-4275     ISO Abbreviation:  Pediatrics     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-12-01     Completed Date:  2009-12-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376422     Medline TA:  Pediatrics     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1556-64     Citation Subset:  AIM; IM    
Affiliation:
Clinic of Neonatology Charit?? Campus Mitte, Charit??-Universit??tsmedizin Berlin, Berlin, Germany .
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MeSH Terms
Descriptor/Qualifier:
Body Burden
Cohort Studies
Female
Humans
Infant, Extremely Low Birth Weight*
Infant, Newborn
Infant, Very Low Birth Weight*
Intensive Care Units, Neonatal*
Length of Stay
Male
Neoplasms, Radiation-Induced / epidemiology
Radiation Dosage*
Radiography / adverse effects*,  utilization
Radiometry / methods
Risk Factors
Utilization Review

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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