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Radiation dose and cancer risk from pediatric CT examinations on 64-slice CT: a phantom study.
MedLine Citation:
PMID:  20363573     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
OBJECTIVE: To measure the radiation dose from CT scans in an anthropomorphic phantom using a 64-slice MDCT, and to estimate the associated cancer risk.
MATERIALS AND METHODS: Organ doses were measured with a 5-year-old phantom and thermoluminescent dosimeters. Four protocols; head CT, thorax CT, abdomen CT and pelvis CT were studied. Cancer risks, in the form of lifetime attributable risk (LAR) of cancer incidence, were estimated by linear extrapolation using the organ radiation doses and the LAR data.
RESULTS: The effective doses for head, thorax, abdomen and pelvis CT, were 0.7mSv, 3.5mSv, 3.0mSv, 1.3mSv respectively. The organs with the highest dose were; for head CT, salivary gland (22.33mGy); for thorax CT, breast (7.89mGy); for abdomen CT, colon (6.62mGy); for pelvis CT, bladder (4.28mGy). The corresponding LARs for boys and girls were 0.015-0.053% and 0.034-0.155% respectively. The organs with highest LARs were; for head CT, thyroid gland (0.003% for boys, 0.015% for girls); for thorax CT, lung for boys (0.014%) and breast for girls (0.069%); for abdomen CT, colon for boys (0.017%) and lung for girls (0.016%); for pelvis CT, bladder for both boys and girls (0.008%).
CONCLUSION: The effective doses from these common pediatric CT examinations ranged from 0.7mSv to 3.5mSv and the associated lifetime cancer risks were found to be up to 0.16%, with some organs of higher radiosensitivity including breast, thyroid gland, colon and lungs.
Authors:
Shi-Ting Feng; Martin Wai-Ming Law; Bingsheng Huang; Sherry Ng; Zi-Ping Li; Quan-Fei Meng; Pek-Lan Khong
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Publication Detail:
Type:  Journal Article     Date:  2010-04-03
Journal Detail:
Title:  European journal of radiology     Volume:  76     ISSN:  1872-7727     ISO Abbreviation:  Eur J Radiol     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  e19-23     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Department of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.
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