Document Detail


Radiation damage to large arteries.
MedLine Citation:
PMID:  6821774     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Little is known about late changes in large arteries after radiotherapy. Much more is known about damage to other organs and tissues. The arterial changes resemble chronic, progressive atherosclerosis which may be due to a combination of periarterial fibrosis, direct damage to the arterial wall, occlusion of vasa vasorum and acceleration of naturally occurring atherosclerosis. Factors that may predispose to arterial occlusion that relate to radiotherapy include maximum tissue dose, beam energy and field size. The authors present four patients with axillary artery occlusion that occurred 10 to 27 years after mastectomy and irradiation. The axillary artery is seldom affected by segmental atherosclerotic occlusive disease. Hence, the cause of the occlusion was most likely the irradiation. All patients did well after bypass grafting.
Authors:
P G Kalman; I H Lipton; J L Provan; P M Walker; J T Miles; H P Yeung
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Canadian journal of surgery. Journal canadien de chirurgie     Volume:  26     ISSN:  0008-428X     ISO Abbreviation:  Can J Surg     Publication Date:  1983 Jan 
Date Detail:
Created Date:  1983-03-11     Completed Date:  1983-03-11     Revised Date:  2007-08-16    
Medline Journal Info:
Nlm Unique ID:  0372715     Medline TA:  Can J Surg     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  88-91     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Arterial Occlusive Diseases / etiology*
Arteriosclerosis / etiology
Axillary Artery*
Breast Neoplasms / radiotherapy*,  surgery
Female
Humans
Mastectomy
Middle Aged
Radiation Injuries
Radiotherapy / adverse effects*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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