| Radial and vertebral bone density in white and black women: evidence for racial differences in premenopausal bone homeostasis. | |
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MedLine Citation:
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PMID: 2778034 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The reasons for a different incidence of osteoporotic fractures in white and black women are unknown. Previous racial comparisons of bone mass have been limited by racial differences in body weight and socioeconomic, health, and nutritional status. This cross-sectional study examined bone density in 105 black and 114 white healthy nonobese women, 24-65 yr old, using dual photon absorptiometry of the lumbar spine and single photon absorptiometry of the distal radius. Bone density at both sites was higher in blacks at all ages than in whites. When adjusted for age and body mass index, mean bone density was 6.5% higher in blacks at both spine and radius (P less than 0.0001). The cross-sectional rate of decline of vertebral bone density was similar between races; however, radial density increased 3.8%/decade (P = 0.03) in premenopausal blacks under age 46 yr, while it declined 3.2%/decade (P = 0.09) in premenopausal whites. The racial difference in slopes in these premenopausal women is significant (P = 0.002). These findings suggest that attainment of higher peak bone mass and delayed onset of bone loss contribute to the lower incidence of osteoporotic fractures in black women. |
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Authors:
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M M Luckey; D E Meier; J P Mandeli; M C DaCosta; M L Hubbard; S J Goldsmith |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The Journal of clinical endocrinology and metabolism Volume: 69 ISSN: 0021-972X ISO Abbreviation: J. Clin. Endocrinol. Metab. Publication Date: 1989 Oct |
Date Detail:
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Created Date: 1989-10-13 Completed Date: 1989-10-13 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0375362 Medline TA: J Clin Endocrinol Metab Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 762-70 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics, Mount Sinai Medical Center, New York, New York 10029. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult African Continental Ancestry Group* Bone and Bones / anatomy & histology, metabolism, radionuclide imaging* European Continental Ancestry Group* Female Homeostasis Humans Longitudinal Studies Menopause* Middle Aged Regression Analysis Spine / radionuclide imaging |
| Grant Support | |
ID/Acronym/Agency:
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IK08-AG-00358-01/AG/NIA NIH HHS; IR01-AG-07113-01/AG/NIA NIH HHS; RR-71/RR/NCRR NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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