Document Detail


Radamycin, a novel thiopeptide produced by streptomyces sp. RSP9. II. Physico-chemical properties and structure determination.
MedLine Citation:
PMID:  12061547     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The new cyclic peptide antibiotic, radamycin (1) and the known thiopeptide methylsulfomycin I (2) have been isolated from the fermentation broth of a Streptomyces sp. RSP9. The structure of radamycin was elucidated by NMR, LC-MS and FAB-MS and was established as a thiopeptide with oxazole and thiazole moieties, and several unusual amino acids.
Authors:
Julián Castro Rodríguez; Gloria González Holgado; Ramón I Santamaría Sánchez; Librada M Cañedo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of antibiotics     Volume:  55     ISSN:  0021-8820     ISO Abbreviation:  J. Antibiot.     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-06-13     Completed Date:  2002-07-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0151115     Medline TA:  J Antibiot (Tokyo)     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  391-5     Citation Subset:  IM    
Affiliation:
Drug Discovery Division, Instituto Biomar S. A., León, Spain.
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MeSH Terms
Descriptor/Qualifier:
Anti-Bacterial Agents / biosynthesis,  chemistry*,  isolation & purification
Magnetic Resonance Spectroscopy
Mass Spectrometry / methods
Molecular Structure
Peptides, Cyclic / biosynthesis,  chemistry*,  isolation & purification
Streptomyces / metabolism*
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents; 0/Peptides, Cyclic; 0/methylsulfomycin I; 0/radamycin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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