| Racial disparity in meconium-stained amniotic fluid and meconium aspiration syndrome in the United States, 1989-2000. | |
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MedLine Citation:
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PMID: 14662213 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To estimate the prevalence of meconium-stained amniotic fluid and meconium aspiration syndrome, as well as the differences in case fatality from meconium aspiration syndrome, between non-Hispanic black and non-Hispanic white infants. METHODS: We studied non-Hispanic black and non-Hispanic white live births with weights greater than 2.5 kg and gestational ages greater than 35 weeks, using the linked US birth and infant death cohorts for three periods: 1989-1991, 1995-1997, and 1998-2000. We used logistic regression to estimate the risks of meconium-stained amniotic fluid and meconium aspiration syndrome and to estimate the case fatality of meconium aspiration syndrome by maternal race, birth weight, period, and pregnancy complications. RESULTS: Risk of meconium-stained amniotic fluid was 80% higher in non-Hispanic blacks when compared with non-Hispanic whites (birth weight-adjusted odds ratio [OR], 1.81, 95% confidence interval [CI] 1.80, 1.82). The prevalence of pregnancy complications did not explain this racial disparity. Risk of meconium aspiration syndrome in non-Hispanic blacks was 67% higher when compared with non-Hispanic whites (birth weight-adjusted OR 1.67, 95% CI 1.64, 1.70). The case fatality rate of meconium aspiration syndrome was similar between non-Hispanic blacks and non-Hispanic whites in the three periods, with rates of 15.5, 15.2, and 11.2 per 1000 in non-Hispanic blacks and 13.5, 11.2, and 10.1 per 1000 in non-Hispanic whites in 1989-1991, 1995-1997, and 1998-2000, respectively. CONCLUSION: Our results suggest that when compared with non-Hispanic whites, non-Hispanic blacks are at significantly greater risk for meconium-stained amniotic fluid and meconium aspiration syndrome but not for meconium aspiration syndrome case fatality. |
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Authors:
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Sudhir Sriram; Stephen N Wall; Babak Khoshnood; Jaideep K Singh; Hui-Lung Hsieh; Kwang-Sun Lee |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 102 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 2003 Dec |
Date Detail:
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Created Date: 2003-12-09 Completed Date: 2004-01-06 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 1262-8 Citation Subset: AIM; IM |
Affiliation:
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Neonatology Section and Center for Perinatal Epidemiology, University of Chicago Children's Hospital, Pritzker School of Medicine, University of Chicago, Chicago, Illinois 60637, USA. ssriram@peds.bsd.uchicago.edu |
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| MeSH Terms | |
Descriptor/Qualifier:
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African Continental Ancestry Group* Amniotic Fluid* Confidence Intervals European Continental Ancestry Group* Female Humans Infant, Newborn Male Meconium* Meconium Aspiration Syndrome / epidemiology, ethnology Odds Ratio Pregnancy Pregnancy Complications / epidemiology Prevalence Risk Factors United States |
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