Document Detail

Racial differences in respiratory-related neonatal mortality among very low birth weight infants.
MedLine Citation:
PMID:  10753242     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To examine racial differences in the secular trends in respiratory-related neonatal mortality among very low birth weight (VLBW) infants in the United States, temporally associated with surfactant availability. DESIGN: Comparison of time trends in African American and non-Hispanic white (NHW) VLBW infants of cause-specific neonatal mortality and neonatal and infant mortality for 2 consecutive 3-year periods. RESULTS: From 1985 to 1988 there was no racial difference in the rate of decline of each mortality outcome. From 1988 to 1991 rates of decline in neonatal mortality caused by respiratory distress syndrome and by all respiratory causes were significantly greater for NHWs compared with African Americans. However, the rate of decline in nonrespiratory neonatal mortality was similar for African Americans and NHWs. Compared with African American VLBW infants, NHWs had a greater rate of decline in both neonatal (31% vs 20%; P <.01) and infant mortality (32% vs 21%; P <.01) during this period. CONCLUSIONS: Between 1988 and 1991, declines in neonatal mortality risks caused by respiratory distress syndrome and all respiratory causes were greater for NHW infants than for African American VLBW infants. The decline in nonrespiratory mortality risk showed no racial differences. These findings suggest possible racial disparities in timely access or racial differences in the efficacy of respiratory treatments for VLBW infants.
D Ranganathan; S Wall; B Khoshnood; J K Singh; K S Lee
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  136     ISSN:  0022-3476     ISO Abbreviation:  J. Pediatr.     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-05-03     Completed Date:  2000-05-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  454-9     Citation Subset:  AIM; IM    
Section of Neonatology, Department of Pediatrics, University of Chicago Children's Hospital, IL 60637, USA.
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MeSH Terms
African Continental Ancestry Group*
Cause of Death / trends
European Continental Ancestry Group*
Infant Mortality / trends*
Infant, Newborn
Infant, Very Low Birth Weight*
Logistic Models
Odds Ratio
Respiratory Distress Syndrome, Newborn / ethnology,  mortality*
United States / epidemiology
Comment In:
J Pediatr. 2000 Apr;136(4):427-8   [PMID:  10753236 ]

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