Document Detail

Racial differences in renal sodium excretion: relationship to hypertension.
MedLine Citation:
PMID:  8465835     Owner:  NLM     Status:  MEDLINE    
Black Americans are more susceptible to hypertension and to renal disease than white Americans. Both normotensive and hypertensive blacks are more apt to have salt-sensitive blood pressure responses to the challenge of a salt load than whites. Moreover, salt sensitivity of blood pressure in both normotensive and hypertensive subjects is associated with a decreased excretory capacity for sodium, implicating the kidney in this phenomenon. Salt sensitivity of blood pressure also is associated with increasing age and, in normotensive subjects, may predict the subsequent development of hypertension. Radical differences in a variety of humoral as well as hemodynamic responses to physical and mental stressors have been identified. The relationships between these observations and renal sodium handling require further investigation.
M H Weinberger
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  American journal of kidney diseases : the official journal of the National Kidney Foundation     Volume:  21     ISSN:  0272-6386     ISO Abbreviation:  Am. J. Kidney Dis.     Publication Date:  1993 Apr 
Date Detail:
Created Date:  1993-05-05     Completed Date:  1993-05-05     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  8110075     Medline TA:  Am J Kidney Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  41-5     Citation Subset:  IM    
Department of Medicine, Indiana University School of Medicine, Indianapolis 46202-5111.
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MeSH Terms
African Continental Ancestry Group
European Continental Ancestry Group*
Hypertension / ethnology*,  physiopathology*
Natriuresis / physiology*
Reference Values
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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