| Racial differences in renal sodium excretion: relationship to hypertension. | |
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MedLine Citation:
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PMID: 8465835 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Black Americans are more susceptible to hypertension and to renal disease than white Americans. Both normotensive and hypertensive blacks are more apt to have salt-sensitive blood pressure responses to the challenge of a salt load than whites. Moreover, salt sensitivity of blood pressure in both normotensive and hypertensive subjects is associated with a decreased excretory capacity for sodium, implicating the kidney in this phenomenon. Salt sensitivity of blood pressure also is associated with increasing age and, in normotensive subjects, may predict the subsequent development of hypertension. Radical differences in a variety of humoral as well as hemodynamic responses to physical and mental stressors have been identified. The relationships between these observations and renal sodium handling require further investigation. |
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Authors:
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M H Weinberger |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: American journal of kidney diseases : the official journal of the National Kidney Foundation Volume: 21 ISSN: 0272-6386 ISO Abbreviation: Am. J. Kidney Dis. Publication Date: 1993 Apr |
Date Detail:
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Created Date: 1993-05-05 Completed Date: 1993-05-05 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 8110075 Medline TA: Am J Kidney Dis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 41-5 Citation Subset: IM |
Affiliation:
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Department of Medicine, Indiana University School of Medicine, Indianapolis 46202-5111. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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African Continental Ancestry Group European Continental Ancestry Group* Humans Hypertension / ethnology*, physiopathology* Natriuresis / physiology* Reference Values |
| Grant Support | |
ID/Acronym/Agency:
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HL14159/HL/NHLBI NIH HHS; HL20034/HL/NHLBI NIH HHS; HL37717/HL/NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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