| Racial differences in disease extent and severity in patients with ulcerative colitis: a retrospective cohort study. | |
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MedLine Citation:
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PMID: 18273704 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Ulcerative colitis (UC) is increasing in African-Americans (AA). The objectives of this study were to assess disease extent and severity in UC by race. METHODS: Disease extent and severity was assessed in UC outpatients evaluated at the University of Maryland and Baltimore VA from 1997 to 2005. RESULTS: About 197 patients were identified; 47 were AA (23%). Of AA, 23% had proctitis, 23% had left-sided colitis, and 53% had extensive colitis compared to 10%, 31%, and 59% of Caucasians, respectively (P = 0.056). African-Americans were less likely to ever receive steroids (45% versus 62%; P = 0.065), be treated with > or = 2 courses of steroids (54% versus 68%; P = 0.242) or be steroid dependant (33% versus 46%; P = 0.304). After adjustment, only female gender (OR 0.32, [0.16-0.66]) and age at diagnosis (OR 2.50, [1.28-4.90]) were associated with extensive colitis. Being seen at UMMS (OR 5.10, [2.60-10.10]) was associated with steroid use. CONCLUSION: Race was not associated with extent of colitis or disease severity in UC. |
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Authors:
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Mark H Flasar; Sandra Quezada; Priti Bijpuria; Raymond K Cross |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2008-02-14 |
Journal Detail:
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Title: Digestive diseases and sciences Volume: 53 ISSN: 0163-2116 ISO Abbreviation: Dig. Dis. Sci. Publication Date: 2008 Oct |
Date Detail:
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Created Date: 2008-09-01 Completed Date: 2008-10-30 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7902782 Medline TA: Dig Dis Sci Country: United States |
Other Details:
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Languages: eng Pagination: 2754-60 Citation Subset: AIM; IM |
Affiliation:
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Veterans Affairs, Maryland Health Care System, Baltimore, MD, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult African Americans / ethnology* Cohort Studies Colectomy Colitis, Ulcerative / drug therapy, ethnology*, surgery European Continental Ancestry Group / ethnology* Female Humans Male Maryland Middle Aged Retrospective Studies Severity of Illness Index* Steroids / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Steroids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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