Document Detail


Rabies postexposure management of travelers presenting to travel health clinics in Auckland and Hamilton, New Zealand.
MedLine Citation:
PMID:  19192122     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Rabies is a fatal disease, and travelers going to endemic areas need to take precautions. Little is known about the rabies postexposure management of travelers from New Zealand. METHODS: A total of 459 post-travel records from October 1998 until February 2006 at two travel medicine clinics, in Auckland and Hamilton, were examined for those who reported postexposure management to animals while abroad. RESULTS: Fifty-four patients were included, 48 (88.9%) were New Zealand residents and 52.0% were male. The mean age of exposed travelers was 30.4 years (SD = 15.5). There was an adult to child ratio of 5:1. The highest exposure risk group was those aged 16 to 30 years. South and Southeast Asia were the most prominent geographical regions where exposure occurred, with 45 (83.3%) of subjects being potentially exposed to rabies. Dogs were the commonest animals involved, accounting for two thirds of incidents (36; 66.7%). The commonest sites of animal exposure on the body were the thigh and lower leg (26; 48.1%) and the hand (10; 18.5%). Forty-six (85.2%) of the animal exposures were graded as World Health Organization (WHO) category III. Forty-nine (90.7%) of the travelers had not had preexposure prophylaxis. Once in New Zealand, the correct WHO postexposure prophylaxis regime was applied on 44 of 52 (84.6%) occasions. However, overall, only 25% of the sample received postexposure treatment consistent with WHO guidelines, reflecting inappropriate management abroad. CONCLUSIONS: Post-travel consultations at two New Zealand travel clinics were analyzed for prophylactic rabies postexposure management. The majority were travelers aged 16 to 30 years, who sustained WHO category III exposures to the lower limb in Asia, predominantly from dogs. Few of these travelers had been immunized prior to travel, and only 25% of them received postexposure prophylaxis consistent with WHO guidelines. Thus, 75% of the study sample remains at theoretical risk of contracting rabies due to inappropriate management overseas.
Authors:
Marc T M Shaw; Brigid O'Brien; Peter A Leggat
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of travel medicine     Volume:  16     ISSN:  1708-8305     ISO Abbreviation:  J Travel Med     Publication Date:    2009 Jan-Feb
Date Detail:
Created Date:  2009-02-04     Completed Date:  2009-06-03     Revised Date:  2009-07-07    
Medline Journal Info:
Nlm Unique ID:  9434456     Medline TA:  J Travel Med     Country:  England    
Other Details:
Languages:  eng     Pagination:  13-7     Citation Subset:  IM    
Affiliation:
Worldwise Travellers Health Centres of New Zealand, Auckland, New Zealand. doctors@worldwise.co.nz
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Ambulatory Care
Animals
Bites and Stings / complications,  virology
Child
Child, Preschool
Databases, Factual
Dogs
Female
Humans
Immunization, Passive*
Immunoglobulins / administration & dosage*
Infant
Infant, Newborn
Male
Middle Aged
New Zealand / epidemiology
Rabies / drug therapy,  epidemiology,  etiology,  prevention & control*
Rabies Vaccines / administration & dosage*
Sentinel Surveillance
Travel*
Young Adult
Chemical
Reg. No./Substance:
0/Immunoglobulins; 0/Rabies Vaccines
Comments/Corrections
Comment In:
J Travel Med. 2009 May-Jun;16(3):227; author reply 227   [PMID:  19538592 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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