| RP-30A: new tracer for detection of changes in testicular blood flow in rat torsion model. | |
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MedLine Citation:
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PMID: 1310551 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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RP-30A is a radioactive tracer being evaluated for the detection of regional myocardial blood flow. This study compares RP-30A to technetium 99m pertechnetate as radioactive tracers for the detection of testicular blood flow changes in early testicular torsion. The left testis of adult male Sprague-Dawley rats was subjected to either thirty or sixty minutes of 720 degrees torsion. Injections of RP-30A or 99mTc-pertechnetate followed by sacrifice and scintillation counting of the testes was performed. No significant difference was detected between the torted testes and the right control testes in both groups receiving 99mTc-pertechnetate and the thirty-minute group receiving RP-30A. The torted testes of the sixty-minute group receiving RP-30A revealed a significant difference (decrease) in uptake indicating that RP-30A may be a more sensitive tracer in detecting testicular blood flow changes in early testicular torsion. |
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Authors:
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J A Motola; S Hoory; A D Smith; B C Mellinger |
Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Urology Volume: 39 ISSN: 0090-4295 ISO Abbreviation: Urology Publication Date: 1992 Feb |
Date Detail:
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Created Date: 1992-03-10 Completed Date: 1992-03-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0366151 Medline TA: Urology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 194-8 Citation Subset: IM |
Affiliation:
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Department of Urology, Long Island Jewish Medical Center, New Hyde Park, New York. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Humans Male Nitriles / diagnostic use* Organotechnetium Compounds / diagnostic use* Rats Rats, Inbred Strains Regional Blood Flow Sodium Pertechnetate Tc 99m / diagnostic use* Spermatic Cord Torsion / radionuclide imaging* Technetium Tc 99m Sestamibi Testis / blood supply* |
| Chemical | |
Reg. No./Substance:
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0/Nitriles; 0/Organotechnetium Compounds; 109581-73-9/Technetium Tc 99m Sestamibi; 23288-60-0/Sodium Pertechnetate Tc 99m |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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