| ROC curve analysis: an example showing the relationships among serum lipid and apolipoprotein concentrations in identifying patients with coronary artery disease. | |
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MedLine Citation:
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PMID: 1643709 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Clinical accuracy, defined as the ability to discriminate between states of health, is the fundamental property of any diagnostic test or system. It is readily expressed as clinical sensitivity and specificity, and elegantly represented by the receiver operating characteristic (ROC) curve. To demonstrate the use of ROC curves, we reexamine a study of the ability of serum lipid and apolipoprotein measures to discriminate among degrees of coronary artery disease in patients undergoing coronary angiography. ROC curve analysis reveals that none of these indexes is highly accurate, but demonstrates a modest increase in the accuracy of apolipoprotein over lipid indexes. |
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Authors:
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M H Zweig; S K Broste; R A Reinhart |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical chemistry Volume: 38 ISSN: 0009-9147 ISO Abbreviation: Clin. Chem. Publication Date: 1992 Aug |
Date Detail:
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Created Date: 1992-09-10 Completed Date: 1992-09-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9421549 Medline TA: Clin Chem Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1425-8 Citation Subset: IM |
Affiliation:
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Clinical Pathology Department, Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, MD 20892. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Apolipoproteins
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blood* Cholesterol / blood Cholesterol, HDL / blood Cholesterol, LDL / blood Coronary Angiography Coronary Disease / blood*, radiography False Positive Reactions Female Humans Lipids / blood* Male Quality Control ROC Curve* |
| Chemical | |
Reg. No./Substance:
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0/Apolipoproteins; 0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Lipids; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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