| RNA sulfurtransferase activity in rat liver and chemically induced hepatomas. | |
| | |
MedLine Citation:
|
PMID: 172228 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
RNA sulfurtransferase activity has been detected in rat liver and in hepatomas from rats fed a diet containing 0.06% 3'-methyl-4-dimethylaminoazobenzene for 14 to 18 weeks. The reaction measured was the transfer of sulfur from cysteine to acceptor sites in Escherichia coli B transfer RNA (tRNA). Specific activities of the enzymes in liver and hepatoma supernatant fractions were similar, as were the rates and extents of sulfur transfer to tRNA. DEAE-cellulose chromatography of digests of the [35S]tRNA reaction products revealed 3 peaks associated with nucleotide material, the amounts of these peaks differing in tRNA from liver and hepatoma systems. This may suggest differences in specific sulfurtransferases in these tissues. |
| | |
Authors:
|
C L Harris; F T Kerns; W St Clair |
Related Documents
:
|
22358528 - Assay systems for screening food components that have anti-proliferative and anti-invas... 16218878 - Degradation of the sodium taurocholate cotransporting polypeptide (ntcp) by the ubiquit... 3621358 - Studies on ornithine decarboxylase from liver, kidney and tumoral tissues during activi... 3917648 - Microsomal monooxygenase system in morris hepatoma: purification and characterization o... 3189778 - Preparation and quantification of 3'-phosphoadenosine 5'-phospho[35s]sulfate with high ... 3114578 - Effect of prostaglandin e2 on the small intestine of indomethacin-treated rats. |
Publication Detail:
|
Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
|
Title: Cancer research Volume: 35 ISSN: 0008-5472 ISO Abbreviation: Cancer Res. Publication Date: 1975 Dec |
Date Detail:
|
Created Date: 1976-02-20 Completed Date: 1976-02-20 Revised Date: 2009-10-27 |
Medline Journal Info:
|
Nlm Unique ID: 2984705R Medline TA: Cancer Res Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 3608-10 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Carcinoma, Hepatocellular / chemically induced, enzymology* Histocytochemistry / methods Liver / enzymology* Liver Neoplasms / chemically induced, enzymology* Male Methyldimethylaminoazobenzene Neoplasms, Experimental / chemically induced, enzymology RNA Rats Sulfurtransferases / metabolism* |
| Chemical | |
Reg. No./Substance:
|
55-80-1/Methyldimethylaminoazobenzene; 63231-63-0/RNA; EC 2.8.1.-/Sulfurtransferases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Focal infection and transformation in situ of thymus cell subclasses by a thymotropic murine leukemi...
Next Document: Polyamine metabolism in normal and in virus-transformed chick embryo fibroblasts.