Document Detail

RNA polymerase II carboxy-terminal domain with multiple connections.
MedLine Citation:
PMID:  17603278     Owner:  NLM     Status:  MEDLINE    
The largest subunit of eukaryotic RNA polymerase II contains a unique domain at its carboxy-terminus, which is referred to as the carboxy-terminal domain (CTD). The CTD is made up of an evolutionarily conserved heptapeptide repeat (YSPTSPS). Over the past decade, there has been increasing attention on the role of the CTD in transcription regulation in the view of mRNA processing and chromatin remodeling. This paper provides a brief overview of the recent progress in the dynamic changes in CTD phosphorylation and its role in integrating multiple nuclear events.
Eun-Jung Cho
Related Documents :
10546888 - Regulated phosphorylation of the rna polymerase ii c-terminal domain (ctd).
21291938 - Anti-legionella activity of staphylococcal hemolytic peptides.
22206968 - Fabrication of hierarchical structures by unconventional two-step imprinting.
16488888 - The structure of cody, a gtp- and isoleucine-responsive regulator of stationary phase a...
8968598 - Effect of cholesterol and charge on pore formation in bilayer vesicles by a ph-sensitiv...
3327868 - Specificity of the immunoadsorbent used for large-scale recovery of interferon alpha-2a.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Experimental & molecular medicine     Volume:  39     ISSN:  1226-3613     ISO Abbreviation:  Exp. Mol. Med.     Publication Date:  2007 Jun 
Date Detail:
Created Date:  2007-07-02     Completed Date:  2007-09-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9607880     Medline TA:  Exp Mol Med     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  247-54     Citation Subset:  IM    
College of Pharmacy, Sungkyunkwan University, Suwon 440-746, Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Amino Acid Motifs
Amino Acid Sequence
Chromatin / physiology*
Chromatin Assembly and Disassembly
Conserved Sequence
Histones / metabolism
Protein Structure, Tertiary
RNA Polymerase II / chemistry,  physiology*
RNA, Messenger / metabolism
Transcription, Genetic
Reg. No./Substance:
0/Chromatin; 0/Histones; 0/RNA, Messenger; EC 2.7.7.-/RNA Polymerase II

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Simultaneous analysis of 17 organochlorine pesticides in natural medicines by GC/MS with negative ch...
Next Document:  Histamine and spontaneously released mast cell granules affect the cell growth of human hepatocellul...