Document Detail

RNA and memory: a re-evaluation of present data.
MedLine Citation:
PMID:  16961014     Owner:  NLM     Status:  MEDLINE    
Studies on the beneficial effects of yeast RNA treatment on learning and memory in senile patients and in animal experimentation are reviewed in this paper. Experimental evidence is cited showing that yeast RNA is not incorporated into brain tissue and does not increase brain synthetic activity. Thus the therapeutic effects of RNA treatment cannot be explained in direct relation to the hypothesis that RNA within the brain encodes memory information. Evidence for stimulant action of RNA, mediated by uric acid, its primary metabolite, is presented as the basis for an alternative theory which would explain RNA action in pharmacological terms.
H E Enesco
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Canadian Psychiatric Association journal     Volume:  12     ISSN:  0008-4824     ISO Abbreviation:  Can Psychiatr Assoc J     Publication Date:  1967 Feb 
Date Detail:
Created Date:  2006-09-11     Completed Date:  2006-10-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0414266     Medline TA:  Can Psychiatr Assoc J     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  29-34     Citation Subset:  IM    
Allan Memorial Institute of Psychiatry, 1025 Pine Ave. W., Montreal.
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MeSH Terms
Memory / drug effects*
RNA / chemistry,  pharmacology*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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