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RNA-ligant interactions. (I) Magnesium binding sites in yeast tRNAPhe.
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MedLine Citation:
PMID:  333395     Owner:  NLM     Status:  MEDLINE    
X-ray crystallagraphic studies studies indicate that there are at least four site-specifically bound hydrated Mg2+ ions, [Mg(H2O)n]2+, in yeast tRNAPhe. The size and the octahedral coordination geometry, rather than the charge, of [Mg(H2O)N]2+ appear to be the primary reasons for the specificity of magnesium ions in site-binding and in the stabilization of the tertiary structure of tRNA.
S R Holbrook; J L Sussman; R W Warrant; G M Church; S H Kim
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Nucleic acids research     Volume:  4     ISSN:  0305-1048     ISO Abbreviation:  Nucleic Acids Res.     Publication Date:  1977 Aug 
Date Detail:
Created Date:  1977-11-30     Completed Date:  1977-11-30     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0411011     Medline TA:  Nucleic Acids Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  2811-20     Citation Subset:  IM    
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MeSH Terms
Binding Sites
Chemical Phenomena
Models, Molecular
Nucleic Acid Conformation
RNA, Transfer*
Saccharomyces cerevisiae
X-Ray Diffraction
Reg. No./Substance:
0/Ligands; 63-91-2/Phenylalanine; 7439-95-4/Magnesium; 9014-25-9/RNA, Transfer

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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Journal Information
Journal ID (nlm-ta): Nucleic Acids Res
ISSN: 0305-1048
ISSN: 1362-4962
Article Information
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Print publication date: Month: 8 Year: 1977
Volume: 4 Issue: 8
First Page: 2811 Last Page: 2820
ID: 342610
PubMed Id: 333395

RNA-ligant interactions. (I) Magnesium binding sites in yeast tRNAPhe.
S R Holbrook
J L Sussman
R W Warrant
G M Church
S H Kim

Article Categories:
  • Research Article

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