| RIG-I-like receptors: cytoplasmic sensors for non-self RNA. | |
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MedLine Citation:
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PMID: 21884169 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Summary: Viral infection results in the generation of non-self RNA species in the cells, which is recognized by retinoic acid inducible gene-I-like receptors (RLRs), and initiates innate antiviral responses, including the production of proinflammatory cytokines and type I interferon. In this review, we summarize reports on virus-specificity of RLRs, structures of non-self RNA patterns, structural biology of RLRs, and the signaling adapter molecules involved in antiviral innate immunity. |
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Authors:
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Hiroki Kato; Kiyohiro Takahasi; Takashi Fujita |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Immunological reviews Volume: 243 ISSN: 1600-065X ISO Abbreviation: Immunol. Rev. Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-09-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7702118 Medline TA: Immunol Rev Country: Denmark |
Other Details:
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Languages: eng Pagination: 91-8 Citation Subset: IM |
Copyright Information:
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© 2011 John Wiley & Sons A/S. |
Affiliation:
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Laboratory of Molecular Genetics, Institute for Virus, Research, Kyoto University, Kyoto, Japan. Laboratory of Molecular Cell Biology, Graduate School of Biostudies, Kyoto University, Kyoto, Japan. Institute for Innovative NanoBio Drug Discovery and Development, Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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