Document Detail


RF pulse optimization for Bloch-Siegert B ₁⁺ mapping.
MedLine Citation:
PMID:  22144397     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The Bloch-Siegert (B-S) method of B ₁⁺ mapping has been shown to be fast and accurate, yet has high SAR and moderately long TE. These limitations can lengthen scan times and incur signal loss due to B(0) inhomogeneity, particularly at high field. The B-S method relies on applying a band-limited off-resonant B-S radiofrequency pulse to induce a B ₁⁺-dependent frequency-shift for resonant spins. A method for optimizing the B-S radiofrequency pulse is presented here, which maximizes B-S B ₁⁺ measurement sensitivity for a given SAR and T(2) . A 4-ms optimized pulse is shown to have 35% less SAR compared with the conventional 6-ms Fermi pulse while still improving B ₁⁺ map angle-to-noise ratio by 22%. The optimized pulse performance is validated both in phantom and in vivo brain imaging at 7 T.
Authors:
Mohammad Mehdi Khalighi; Brian K Rutt; Adam B Kerr
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2011-12-05
Journal Detail:
Title:  Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine     Volume:  68     ISSN:  1522-2594     ISO Abbreviation:  Magn Reson Med     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-08-28     Completed Date:  2013-01-25     Revised Date:  2014-04-16    
Medline Journal Info:
Nlm Unique ID:  8505245     Medline TA:  Magn Reson Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  857-62     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Wiley Periodicals, Inc.
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MeSH Terms
Descriptor/Qualifier:
Algorithms*
Brain / anatomy & histology*
Humans
Image Enhancement / methods*
Image Interpretation, Computer-Assisted / methods*
Phantoms, Imaging
Radio Waves
Reproducibility of Results
Sensitivity and Specificity
Grant Support
ID/Acronym/Agency:
P41 RR009784/RR/NCRR NIH HHS; P41 RR009784-15/RR/NCRR NIH HHS; P41RR09784/RR/NCRR NIH HHS; R01 EB005307/EB/NIBIB NIH HHS; R01 EB005307-03/EB/NIBIB NIH HHS; R01 EB008108/EB/NIBIB NIH HHS; R01 EB008108-05/EB/NIBIB NIH HHS; R01EB005307/EB/NIBIB NIH HHS; R01EB008108/EB/NIBIB NIH HHS; R33 CA118276/CA/NCI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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