Document Detail


REM sleep behavior disorder, hallucinations, and cognitive impairment in Parkinson's disease.
MedLine Citation:
PMID:  16228998     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The objective of this study was to evaluate the relationship between REM sleep behavior disorder (RBD), hallucinations, and cognitive impairment in Parkinson's disease (PD). One hundred and ten PD patients, divided into three groups (without RBD or hallucinations; with RBD but no hallucinations; with RBD and hallucinations), were submitted to neuropsychological evaluation. The group without RBD and hallucinations showed normal neuropsychological tests when compared to normal controls. The group with hallucinations was characterized by a more severe cognitive impairment affecting both short- and long-term memory, logical abilities, and frontal functions, while the RBD-only group presented frontal impairment. The hypothesis that RBD in PD can be considered a risk factor not only of the hallucinations but also of more severe and diffuse cognitive abnormalities needs to be strengthened through a longitudinal evaluation.
Authors:
Elena Sinforiani; Roberta Zangaglia; Raffaele Manni; Silvano Cristina; Enrico Marchioni; Giuseppe Nappi; Francesca Mancini; Claudio Pacchetti
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Movement disorders : official journal of the Movement Disorder Society     Volume:  21     ISSN:  0885-3185     ISO Abbreviation:  Mov. Disord.     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-04-17     Completed Date:  2006-09-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8610688     Medline TA:  Mov Disord     Country:  United States    
Other Details:
Languages:  eng     Pagination:  462-6     Citation Subset:  IM    
Copyright Information:
Copyright 2005 Movement Disorder Society.
Affiliation:
Laboratory of Neuropsychology, IRCCS C. Mondino Institute of Neurology, Pavia, Italy. elena.sinforiani@mondino.it
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MeSH Terms
Descriptor/Qualifier:
Aged
Cognition Disorders / complications*
Female
Hallucinations / complications*
Humans
Male
Mental Status Schedule
Middle Aged
Multivariate Analysis
Neuropsychological Tests
Parkinson Disease / complications*
REM Sleep Behavior Disorder / complications*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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