| RDS and tracheal phospholipid composition in twins: independent of gestational age. | |
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MedLine Citation:
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PMID: 576875 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The surfactant phospholipids in the tracheal effluent of eight pairs of preterm twins were followed, serially. In four pairs only one of the twins had RDS; in the other four pairs both twins had RDS. Twins with and without RDS had markedly different surfactant phospholipids. Phosphatidylglycerol was absent in all twins with RDS. L/S ratios in tracheal effluent increased after birth in infants with and without RDS. With recovery from RDS, phosphatidylinositol increased. The study helps confirm previous studies of the necessity of the acidic phospholipids, PI and PG, in stabilizing lecithin, as well as that surfactant composition can be independent of gestational age. |
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Authors:
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M Obladen; L Gluck |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The Journal of pediatrics Volume: 90 ISSN: 0022-3476 ISO Abbreviation: J. Pediatr. Publication Date: 1977 May |
Date Detail:
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Created Date: 1977-06-11 Completed Date: 1977-06-11 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0375410 Medline TA: J Pediatr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 799-802 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Body Composition Diseases in Twins* Female Gestational Age Humans Infant, Newborn Male Phosphatidylglycerols / analysis Phosphatidylinositols / analysis Phosphatidylserines / analysis Pulmonary Surfactants / analysis*, biosynthesis Respiratory Distress Syndrome, Newborn / metabolism* Trachea / analysis* |
| Chemical | |
Reg. No./Substance:
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0/Phosphatidylglycerols; 0/Phosphatidylinositols; 0/Phosphatidylserines; 0/Pulmonary Surfactants |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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