| RAMP: A Bioinformatics Framework for Researching Imaging Agents through Molecular Pathways. | |
| | |
MedLine Citation:
|
PMID: 23348786 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
AbstractSignaling pathways are the fundamental grammar of cellular communication, yet few frameworks are available to analyze molecular imaging probes in the context of signaling pathways. Such a framework would aid in the design and selection of imaging probes for measuring specific signaling pathways and, vice versa, help illuminate which pathways are being assayed by a given probe. RAMP (Researching imaging Agents through Molecular Pathways) is a bioinformatics framework for connecting signaling pathways and imaging probes using a controlled vocabulary of the imaging targets. RAMP contains signaling pathway data from MetaCore, the Kyoto Encyclopedia of Genes and Genomes, and the Gene Ontology project; imaging probe data from the Molecular Imaging and Contrast Agent Database (MICAD); and tissue protein expression data from The Human Protein Atlas. The RAMP search tool is available at <http://www.rampsearch.com>. Examples are presented to demonstrate the utility of RAMP for pathway-based searches of molecular imaging probes. |
| | |
Authors:
|
Edward Khokhlovich; Daniel Wahl; Anthony Masiello; Pierre Parisot; Stefan El-Ghatta; Joseph D Szustakowski; Nanguneri Nirmala; David S Tuch |
Related Documents
:
|
18810066 - Us and european risser grading systems: which one best predict the curve acceleration p... 9022726 - Enhancing the performance of the autopap 300 qc system with optimal staining and presen... 17405466 - Agreement amongst examiners assessing dental fluorosis from digital photographs using t... 22843386 - Imaging cellulose using atomic force microscopy. 17621326 - Computed tomography with linear shift-invariant optical systems. 9057926 - Fuzzy systems approach to diagnosis in the postpartum cow. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Molecular imaging Volume: 12 ISSN: 1536-0121 ISO Abbreviation: Mol Imaging Publication Date: 2013 Feb |
Date Detail:
|
Created Date: 2013-01-25 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101120118 Medline TA: Mol Imaging Country: United States |
Other Details:
|
Languages: eng Pagination: 2-7 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Distinguishing between Indirect and Direct Modes of Transmission Using Epidemiological Time Series.
Next Document: In Vivo Imaging of Brain Infarct with the Novel Fluorescent Probe PSVue 794 in a Rat Middle Cerebral...