Document Detail

R-wave amplitude response to myocardial ischemia in hypertrophic cardiomyopathy.
MedLine Citation:
PMID:  17884073     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND PURPOSE: R-wave amplitude change during exercise has been reported to enhance diagnostic value for myocardial ischemia in coronary heart disease. METHODS: We summed up R-wave amplitude in all the 12 leads during exercise testing and correlated the results with regional myocardial ischemia or diffuse subendocardial ischemia as detected by scintigraphy in 49 patients with hypertrophic cardiomyopathy (HCM) and 16 controls. RESULTS: The sum of R-wave amplitude decreased during exercise in patients with HCM (mean, 12.4 mV to 11.7 mV, P < .01) as well as in controls (8.0 mV to 7.7 mV, P < .05). Percent changes in the sum of R-wave amplitude did not differ between 4 subgroups of patients with HCM: one having both regional and subendocardial ischemia, one only the former, one only the latter, and one neither of them (mean, 6.5%, 7.7%, 4.6%, and 5.1%; P = .79). CONCLUSIONS: R-wave amplitude response to exercise failed to demonstrate myocardial ischemia in our patients with HCM.
Tatsuya Kawasaki; Yoshiki Akakabe; Michiyo Yamano; Shigeyuki Miki; Tadaaki Kamitani; Toshiro Kuribayashi; Hiroki Sugihara
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Publication Detail:
Type:  Comparative Study; Journal Article     Date:  2007-09-19
Journal Detail:
Title:  Journal of electrocardiology     Volume:  41     ISSN:  1532-8430     ISO Abbreviation:  J Electrocardiol     Publication Date:    2008 Jan-Feb
Date Detail:
Created Date:  2008-01-14     Completed Date:  2008-02-04     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  68-71     Citation Subset:  IM    
Department of Cardiology, Matsushita Memorial Hospital, Osaka, Japan.
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MeSH Terms
Cardiomyopathy, Hypertrophic / complications*,  diagnosis*
Diagnosis, Computer-Assisted / methods*
Electrocardiography / methods*
Exercise Test
Middle Aged
Myocardial Ischemia / complications*,  diagnosis*
Reproducibility of Results
Sensitivity and Specificity

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